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FGF8 fibroblast growth factor 8 [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100432789, updated on 3-Apr-2024

Summary

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Gene symbol
FGF8
Gene description
fibroblast growth factor 8
Locus tag
CR201_G0023542
See related
Ensembl:ENSPPYG00000002588
Gene type
protein coding
RefSeq status
MODEL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 8 NC_071993.2 (108722062..108727940, complement)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 10 NC_071995.1 (104899187..104905152, complement)

Chromosome 8 - NC_071993.2Genomic Context describing neighboring genes Neighboring gene small ribosomal subunit protein eS8-like Neighboring gene uncharacterized LOC134762073 Neighboring gene uncharacterized LOC129048475 Neighboring gene nucleophosmin/nucleoplasmin 3 Neighboring gene O-GlcNAcase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables fibroblast growth factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in dorsal/ventral pattern formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in embryonic heart tube development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heart morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in limb morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibroblast growth factor 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_071993.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    108722062..108727940 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024254289.3 → XP_024110057.1  fibroblast growth factor 8 isoform X4

    UniProtKB/TrEMBL
    A0A2J8XYD0
    Conserved Domains (1) summary
    pfam00167
    Location:41 → 164
    FGF; Fibroblast growth factor

  2. XM_024254288.3 → XP_024110056.1  fibroblast growth factor 8 isoform X3

    UniProtKB/TrEMBL
    A0A2J8XYE1, H2NBD7
    Related
    ENSPPYP00000003008.2
    Conserved Domains (1) summary
    pfam00167
    Location:52 → 175
    FGF; Fibroblast growth factor

  3. XM_024254287.3 → XP_024110055.3  fibroblast growth factor 8 isoform X2

    UniProtKB/TrEMBL
    A0A2J8XYG5

  4. XM_024254286.3 → XP_024110054.3  fibroblast growth factor 8 isoform X1

    UniProtKB/TrEMBL
    A0A2J8XYE8, H2NBD8
Nucleotide Protein
Heading Accession and Version

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