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TMPRSS4 transmembrane serine protease 4 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100355162, updated on 8-Mar-2024

Summary

Gene symbol
TMPRSS4
Gene description
transmembrane serine protease 4
See related
Ensembl:ENSOCUG00000016983
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
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Genomic context

Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) Unplaced Scaffold NW_026259223.1 (963715..1001256, complement)

NW_026259223.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC127488149 Neighboring gene sodium voltage-gated channel beta subunit 4 Neighboring gene small integral membrane protein 35 Neighboring gene interleukin 10 receptor subunit alpha

Genomic regions, transcripts, and products

Genomic Sequence:
NW_026259223 Unplaced Scaffold Reference UM_NZW_1.0 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
transmembrane protease serine 4
Names
transmembrane protease, serine 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NW_026259223.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    963715..1001256 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008249423.3XP_008247645.1  transmembrane protease serine 4

    UniProtKB/TrEMBL
    A0A5F9CDL4, G1TCR7
    Related
    ENSOCUP00000014592.3
    Conserved Domains (4) summary
    smart00020
    Location:204429
    Tryp_SPc; Trypsin-like serine protease
    cd00112
    Location:5690
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:205432
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    cl02509
    Location:106200
    SRCR_2; Scavenger receptor cysteine-rich domain