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ACVR1B activin A receptor type 1B [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100345068, updated on 6-Jun-2024

Summary

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Gene symbol
ACVR1B
Gene description
activin A receptor type 1B
See related
Ensembl:ENSOCUG00000017934
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 4 NC_067377.1 (43697992..43735911)

Chromosome 4 - NC_067377.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 33 Neighboring gene translation initiation factor IF-2 Neighboring gene activin A receptor like type 1 Neighboring gene trafficking regulator and scaffold protein tamalin Neighboring gene nuclear receptor subfamily 4 group A member 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067377.1 Chromosome 4 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables activin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables activin receptor activity, type I IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of activin receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
activin receptor type-1B
Names
activin A receptor, type IB

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067377.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    43697992..43735911
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_051845502.1 → XP_051701462.1  activin receptor type-1B isoform X3

  2. XM_051845500.1 → XP_051701460.1  activin receptor type-1B isoform X1

    UniProtKB/TrEMBL
    G1TES4

  3. XM_051845501.1 → XP_051701461.1  activin receptor type-1B isoform X2

    UniProtKB/TrEMBL
    G1TES4

  4. XM_017341873.2 → XP_017197362.1  activin receptor type-1B isoform X2

    UniProtKB/TrEMBL
    G1TES4
    Related
    ENSOCUP00000015408.4
    Conserved Domains (4) summary
    smart00220
    Location:157 → 440
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14143
    Location:159 → 446
    STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors
    pfam01064
    Location:8 → 57
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:126 → 153
    TGF_beta_GS; Transforming growth factor beta type I GS-motif
Nucleotide Protein
Heading Accession and Version

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