aff2 AF4/FMR2 family, member 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: aff2provided by ZNC
Official Full Name: AF4/FMR2 family, member 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-110411-190
See related: Ensembl:ENSDARG00000052242 AllianceGenome:ZFIN:ZDB-GENE-110411-190
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-76h4.1
Summary: Predicted to enable G-quadruplex RNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to act upstream of or within regulation of gene expression. Predicted to be located in nucleus. Predicted to be active in nuclear speck. Is expressed in intermediate cell mass of mesoderm. Human ortholog(s) of this gene implicated in X-linked intellectual developmental disorder 109. Orthologous to human AFF2 (ALF transcription elongation factor 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (20342647..20729163)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (20045251..20431783)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables G-quadruplex RNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of RNA splicing	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of gene expression	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nuclear speck	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
NOT part_of super elongation complex	IBA Inferred from Biological aspect of Ancestor more info