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aff2 AF4/FMR2 family, member 2 [ Danio rerio (zebrafish) ]

Gene ID: 100330019, updated on 27-Mar-2024

Summary

Official Symbol
aff2provided by ZNC
Official Full Name
AF4/FMR2 family, member 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-110411-190
See related
Ensembl:ENSDARG00000052242 AllianceGenome:ZFIN:ZDB-GENE-110411-190
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-76h4.1
Summary
Predicted to enable G-quadruplex RNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be located in nucleus. Predicted to be active in nuclear speck. Is expressed in intermediate cell mass of mesoderm. Human ortholog(s) of this gene implicated in X-linked intellectual developmental disorder 109. Orthologous to human AFF2 (AF4/FMR2 family member 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See aff2 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
21
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (20342508..20729311)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (20045251..20431783)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene fragile X messenger ribonucleoprotein 1 Neighboring gene paraneoplastic antigen Ma1 homolog Neighboring gene uncharacterized LOC110440206 Neighboring gene lysozyme g-like 1 Neighboring gene iduronate 2-sulfatase

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables G-quadruplex RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in regulation of RNA splicing IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in nuclear speck IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
NOT part_of super elongation complex IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    20342508..20729311
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002664383.5XP_002664429.2  AF4/FMR2 family member 2

    UniProtKB/TrEMBL
    A0A8M1RDZ7, E7F2E1
    Related
    ENSDARP00000068559.5, ENSDART00000074070.7
    Conserved Domains (1) summary
    pfam05110
    Location:211266
    AF-4; AF-4 proto-oncoprotein