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MIR374A microRNA mir-374a [ Equus caballus (horse) ]

Gene ID: 100314942, updated on 15-Aug-2024

Summary

Gene symbol
MIR374A
Gene description
microRNA mir-374a
See related
Ensembl:ENSECAG00000025995 miRBase:MI0012959
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Also known as
eca-mir-374a
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

Location:
chromosome: X
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) X NC_009175.3 (58620768..58620839, complement)

Chromosome X - NC_009175.3Genomic Context describing neighboring genes Neighboring gene microRNA mir-374b Neighboring gene microRNA mir-545 Neighboring gene zinc finger CCHC-type containing 13 Neighboring gene solute carrier family 16 member 2

Genomic regions, transcripts, and products

Genomic Sequence:
NC_009175.3 Chromosome X Reference EquCab3.0 Primary Assembly

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_033087.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    PJAA01000001
    Related
    ENSECAT00000028007.2

RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009175.3 Reference EquCab3.0 Primary Assembly

    Range
    58620768..58620839 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)