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MIR22 microRNA mir-22 [ Equus caballus (horse) ]

Gene ID: 100314845, updated on 15-Feb-2023

Summary

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Gene symbol
MIR22
Gene description
microRNA mir-22
See related
Ensembl:ENSECAG00000026466 miRBase:MI0012778
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Also known as
eca-mir-22
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

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Location:
chromosome: 11
Exon count:
1
Annotation release Status Assembly Chr Location
103 current EquCab3.0 (GCF_002863925.1) 11 NC_009154.3 (45699954..45700038, complement)
102 previous assembly EquCab2.0 (GCF_000002305.2) 11 NC_009154.2 (45377845..45377929, complement)

Chromosome 11 - NC_009154.3Genomic Context describing neighboring genes Neighboring gene pre-mRNA processing factor 8 Neighboring gene 40S ribosomal protein S15a pseudogene Neighboring gene TLC domain containing 2 Neighboring gene WD repeat domain 81 Neighboring gene serpin family F member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. In silico detection and characteristics of novel microRNA genes in the Equus caballus genome using an integrated ab initio and comparative genomic approach. Zhou M, et al. Genomics, 2009 Aug. PMID 19406225
  2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • microRNA 22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_032906.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    PJAA01000012
    Related
    ENSECAT00000028478.2

RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009154.3 Reference EquCab3.0 Primary Assembly

    Range
    45699954..45700038 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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