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PLCD4 phospholipase C delta 4 [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100171640, updated on 6-Jun-2024

Summary

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Gene symbol
PLCD4
Gene description
phospholipase C delta 4
Locus tag
CR201_G0032330
See related
Ensembl:ENSPPYG00000013177
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 11 NC_071996.2 (122039997..122070382)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 2B NC_071987.1 (119396428..119426806)

Chromosome 11 - NC_071996.2Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 37 Neighboring gene uncharacterized LOC134759622 Neighboring gene U6 spliceosomal RNA Neighboring gene CCR4-NOT transcription complex subunit 9 Neighboring gene small nucleolar RNA U3 Neighboring gene zinc finger protein 142 Neighboring gene mitochondrial chaperone BCS1 Neighboring gene ring finger protein 25

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • DKFZp469D0224

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4
Names
PLC-delta-4
phosphoinositide phospholipase C-delta-4
NP_001124787.1
XP_024098625.1
XP_054404451.1
XP_054404452.1
XP_054404453.1
XP_054404454.1
XP_054404455.1
XP_054404456.1
XP_054404457.1
XP_054404458.1
XP_054404459.1
XP_063568471.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001131315.2 → NP_001124787.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4

    See identical proteins and their annotated locations for NP_001124787.1

    Status: PROVISIONAL

    Source sequence(s)
    CR857436
    UniProtKB/Swiss-Prot
    Q5RET0
    UniProtKB/TrEMBL
    A0A2J8TU08, A0A6D2XU01, H2P8L2
    Related
    ENSPPYP00000014724.2, ENSPPYT00000015321.3
    Conserved Domains (8) summary
    cd00275
    Location:626 → 751
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    PLN02952
    Location:207 → 749
    PLN02952; phosphoinositide phospholipase C
    cd13363
    Location:18 → 133
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    pfam00169
    Location:17 → 123
    PH; PH domain
    pfam09279
    Location:207 → 289
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    pfam13499
    Location:143 → 199
    EF-hand_7; EF-hand domain pair
    pfam14788
    Location:153 → 202
    EF-hand_10; EF hand
    cl14615
    Location:289 → 596
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily

RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_071996.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    122039997..122070382
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063712401.1 → XP_063568471.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X6

  2. XM_054548483.2 → XP_054404458.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X4

    UniProtKB/TrEMBL
    A0A8I5TA46

  3. XM_054548476.2 → XP_054404451.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1

    UniProtKB/TrEMBL
    A0A2J8TU08, A0A6D2XU01, H2P8L2

  4. XM_054548479.2 → XP_054404454.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1

    UniProtKB/TrEMBL
    A0A2J8TU08, A0A6D2XU01, H2P8L2

  5. XM_054548477.2 → XP_054404452.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1

    UniProtKB/TrEMBL
    A0A2J8TU08, A0A6D2XU01, H2P8L2

  6. XM_054548480.2 → XP_054404455.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X2

    UniProtKB/TrEMBL
    A0A2J8TU08, A0A2J8TU49, A0A6D2XU01, A0A8I5TZ82, H2P8L2

  7. XM_054548482.2 → XP_054404457.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X2

    UniProtKB/TrEMBL
    A0A2J8TU08, A0A2J8TU49, A0A6D2XU01, A0A8I5TZ82, H2P8L2

  8. XM_024242857.3 → XP_024098625.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X3

    UniProtKB/TrEMBL
    A0A2J8TU08, A0A6D2XU01, H2P8L2
    Conserved Domains (5) summary
    cd00275
    Location:626 → 777
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd13363
    Location:18 → 133
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    cd15898
    Location:138 → 167
    EFh_PI-PLC; EF-hand motif [structural motif]
    cl14615
    Location:289 → 596
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
    cl28895
    Location:138 → 277
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes

  9. XM_054548484.2 → XP_054404459.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X5

    UniProtKB/TrEMBL
    A0A8I5TA46

  10. XM_054548481.2 → XP_054404456.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X2

    UniProtKB/TrEMBL
    A0A2J8TU08, A0A2J8TU49, A0A6D2XU01, A0A8I5TZ82, H2P8L2

  11. XM_054548478.2 → XP_054404453.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1

    UniProtKB/TrEMBL
    A0A2J8TU08, A0A6D2XU01, H2P8L2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5RET0.1 GenPept UniProtKB/Swiss-Prot:Q5RET0

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