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SYCE1L synaptonemal complex central element protein 1 like [ Homo sapiens (human) ]

Gene ID: 100130958, updated on 5-Jan-2022

Summary

Official Symbol
SYCE1Lprovided by HGNC
Official Full Name
synaptonemal complex central element protein 1 likeprovided by HGNC
Primary source
HGNC:HGNC:37236
See related
Ensembl:ENSG00000205078
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MRP2
Summary
Predicted to be involved in synaptonemal complex assembly. Located in intermediate filament cytoskeleton. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Ubiquitous expression in prostate (RPKM 20.9), urinary bladder (RPKM 20.3) and 23 other tissues See more
Orthologs
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Genomic context

See SYCE1L in Genome Data Viewer
Location:
16q23.1
Exon count:
11
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (77199408..77213215)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (77233305..77247112)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene mitotic spindle assembly checkpoint protein MAD2A pseudogene Neighboring gene microRNA 4719 Neighboring gene MON1 homolog B, secretory trafficking associated Neighboring gene vomeronasal 2 receptor 10, pseudogene Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 18

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in synaptonemal complex assembly IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in intermediate filament cytoskeleton IDA
Inferred from Direct Assay
more info
 
is_active_in synaptonemal complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
synaptonemal complex central element protein 1-like
Names
meiosis-related protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001129979.3NP_001123451.1  synaptonemal complex central element protein 1-like isoform 1

    See identical proteins and their annotated locations for NP_001123451.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC009139
    Consensus CDS
    CCDS45533.1
    UniProtKB/Swiss-Prot
    A8MT33
    Related
    ENSP00000367911.4, ENST00000378644.5
    Conserved Domains (1) summary
    pfam15233
    Location:47164
    SYCE1; Synaptonemal complex central element protein 1
  2. NM_001348924.2NP_001335853.1  synaptonemal complex central element protein 1-like isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks two alternate in-frame exons compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    AC009139
    Conserved Domains (1) summary
    pfam15233
    Location:47123
    SYCE1; Synaptonemal complex central element protein 1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    77199408..77213215
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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