AQP7 aquaporin 7 [Sus scrofa (pig)] - Gene

Summary

Gene symbol: AQP7
Gene description: aquaporin 7
See related: Ensembl:ENSSSCG00000010992
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as: SAQP7
Expression: Biased expression in subcutaneous adipose (RPKM 57.3), kidney (RPKM 16.6) and 3 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	10	NC_010452.4 (33098746..33130245)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	10	NC_010452.3 (37361028..37376629)

Chromosome 10 - NC_010452.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data suggest that boar spermatozoa express AQP11 and AQP7; amounts of AQP11 (but not those of AQP7) are correlated with sperm motility, membrane integrity, and membrane fluidity. These studies were conducted in Spain in Pietrain boars.
Title: Aquaporins 7 and 11 in boar spermatozoa: detection, localisation and relationship with sperm quality.
The full length coding sequences of porcine (Sus scrofa) AQP3, 7 and 9 and the genomic sequence of AQP3 including 6 exons and 5 introns, was cloned.
Title: Molecular characterization, chromosomal and expression patterns of three aquaglyceroporins (AQP3, 7, 9) from pig.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables glycerol channel activity	IEA Inferred from Electronic Annotation more info	PubMed
enables urea transmembrane transporter activity	IEA Inferred from Electronic Annotation more info	PubMed
enables water channel activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in glycerol transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in water transport	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in basolateral plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: aquaporin-7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001113438.1 → NP_001106909.1 aquaporin-7

See identical proteins and their annotated locations for NP_001106909.1

Status: PROVISIONAL

Source sequence(s)

EU024116

UniProtKB/TrEMBL

A0A4X1UQS3, A0A8D0YG57, A0A8D1E4G2, A9Y007, F6Q0L3

Related

ENSSSCP00000040430.1, ENSSSCT00000042660.3

Conserved Domains (1) summary

cl00200
Location:22 → 279

MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

NC_010452.4 Reference Sscrofa11.1 Primary Assembly

Range

33098746..33130245

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021063972.1 → XP_020919631.1 aquaporin-7 isoform X4

UniProtKB/TrEMBL

A0A8D1N815

Conserved Domains (1) summary

cl00200
Location:22 → 250

MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...
XM_013980180.2 → XP_013835634.1 aquaporin-7 isoform X1

UniProtKB/TrEMBL

A0A4X1UQS3, A0A8D0YG57, A0A8D1E4G2, A9Y007, F6Q0L3

Conserved Domains (1) summary

cl00200
Location:22 → 279

MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...
XM_013980182.2 → XP_013835636.1 aquaporin-7 isoform X3

UniProtKB/TrEMBL

A0A8D0JXH6, A0A8D0YG57, F6Q0L3

Conserved Domains (1) summary

cd00333
Location:2 → 217

MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...
XM_013980181.2 → XP_013835635.1 aquaporin-7 isoform X2

UniProtKB/TrEMBL

A0A4X1URD6, A0A8D0YG57, F6Q0L3

Related

ENSSSCP00000011725.3, ENSSSCT00000012033.5

Conserved Domains (1) summary

cl00200
Location:4 → 261

MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...
XM_013980183.2 → XP_013835637.1 aquaporin-7 isoform X3

UniProtKB/TrEMBL

A0A8D0JXH6, A0A8D0YG57, F6Q0L3

Conserved Domains (1) summary

cd00333
Location:2 → 217

MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...
XM_013980184.2 → XP_013835638.1 aquaporin-7 isoform X3

UniProtKB/TrEMBL

A0A8D0JXH6, A0A8D0YG57, F6Q0L3

Conserved Domains (1) summary

cd00333
Location:2 → 217

MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...