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Zcwpw2 zinc finger, CW type with PWWP domain 2 [ Mus musculus (house mouse) ]

Gene ID: 100039681, updated on 11-Apr-2024

Summary

Official Symbol
Zcwpw2provided by MGI
Official Full Name
zinc finger, CW type with PWWP domain 2provided by MGI
Primary source
MGI:MGI:1921888
See related
Ensembl:ENSMUSG00000032443 AllianceGenome:MGI:1921888
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4930430K04Rik
Summary
Predicted to enable methylated histone binding activity. Predicted to be active in nucleus. Orthologous to human ZCWPW2 (zinc finger CW-type and PWWP domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See Zcwpw2 in Genome Data Viewer
Location:
9 F3; 9 69.83 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (117752903..117869927, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (117923835..118040859, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene RNA binding motif, single stranded interacting protein Neighboring gene predicted gene, 39450 Neighboring gene predicted gene, 26614 Neighboring gene STARR-seq mESC enhancer starr_25450 Neighboring gene predicted gene, 50606 Neighboring gene STARR-positive B cell enhancer ABC_E3864 Neighboring gene STARR-positive B cell enhancer ABC_E2921 Neighboring gene STARR-positive B cell enhancer mm9_chr9:117962449-117962749 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:118059288-118059397 Neighboring gene 5-azacytidine induced gene 2 Neighboring gene C-X9-C motif containing 1 Neighboring gene predicted gene, 17399

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Clone Names

  • MGC129466, MGC141053

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables methylated histone binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables methylated histone binding ISO
Inferred from Sequence Orthology
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
zinc finger CW-type PWWP domain protein 2 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001378466.1NP_001365395.1  zinc finger CW-type PWWP domain protein 2 homolog

    Status: VALIDATED

    Source sequence(s)
    AC157475, AC165253
    UniProtKB/Swiss-Prot
    A0A5F8MP94, Q08EN7
    Related
    ENSMUSP00000158867.2, ENSMUST00000238919.2
    Conserved Domains (2) summary
    pfam07496
    Location:1462
    zf-CW; CW-type Zinc Finger
    cl02554
    Location:82155
    PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    117752903..117869927 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)