Conserved Protein Domain Family
T2SSM

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pfam04612: T2SSM 
Type II secretion system (T2SS), protein M
This family of membrane proteins consists of Type II secretion system protein M sequences from several Gram-negative (diderm) bacteria. The precise function of these proteins is unknown, though in Vibrio cholerae, the T2SM (EpsM) protein interacts with the T2SL (EpsL) protein, and also forms homodimers.
Statistics
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PSSM-Id: 428034
Aligned: 29 rows
Threshold Bit Score: 86.6119
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_011815172   10 RAEAERFWSARNPRERWLLGSGGLLVLVVVPYVAVWEPLTERRDQLQAQVAEQRQDLAWMRSAAEEIHAHD-GDNGSAEP 88  Halorhodospira...
jgi:Mpe_A3134  13 SEQWRARWRRMARRERRLITAAAIVVGVALVWMLGVQPAWRSLRDTPAQIDAVEFQLQQMQRQAAEARELR-KLPTVKPA 91 
jgi:Swit_2585  17 RQKAIGLWQARSRREQWLLGGLAAMVALYVLVAMVILPVQRARAQALSDIRTYESLSARLRSAGPLGQ-----APAQPQA 91 
Q2Y7T4          2 RKQLRKAWESRSPRERRVITILGMILSAGL-YLGLVSSADRARTRLRSNLPQLRVQAEEFEQQAAEYERIK-VTPSPPPL 79  Nitrosospira m...
Q0K5X1         40 QERFNAFWSARNPREQAILAGGGALLALVIGYLVLWEPAADGRERLARNLPKLRADLAEMESLAQEARGLK-ATPAPALR 118 Cupriavidus ne...
Q1LHW4         25 REQVDVFWTARNPREQAILGGGAVVLVLVFGYLLLWEPASVEGARLMRNLPVLRADLAEMETLAQEARGLS-ANRAPSLR 103 Cupriavidus me...
Q13SJ8          6 aQTWAGFWDQRTEREKTLLAWGGGVLSVVIAWSVLWSPAQEGRAHLRESLPTLQRQLAQMTAQANEARQLSaAAQGVAPT 85  Paraburkholder...
Q9I5P1         22 llRLQAYWRQLAPRERKILAGGGLALCLALTWQVFVDPPLARIEHWQAELPRLRAQAAAVDGVLREVEALR----GPTLS 97  Pseudomonas ae...
Q9ABP4          5 LEAARLWWTGRTGREQVLLAVMVAALVVVIGWYGVATPLWSAAKTAQVRVDKAATQLATLRGLAA-------GASRATAG 77  Caulobacter vi...
WP_012133069    5 IAQLKARYQNYSDRERGLITLCAAAMCCAVIYYGGIIPLDHMIQNSQSTLMRQKETLRWMRDEIDKNH-----LQAKVLK 79  Citrobacter
WP_011815172   89 VTderSLLSLVDRAAREAGIddQLSRVQPDGDgTLRVWMDRVPFDELMNWLDGLQrAAGVEVDALTVERTq--------- 159 Halorhodospira...
jgi:Mpe_A3134  92 QA-----EAALRGATERLG---TNARLTLQGD-RATLTLSGVPGEALAAWLGEVRsAARARPDEAKLSHG---------- 152
jgi:Swit_2585  92 GG---SPAAVLSASAARFGM----VPVVNEGGeGIRVTVADAPYESLLRWIAEVEqTSRLRVVRLRLDRRp--------- 155
Q2Y7T4         80 SG---DLHALAQTQADILGLshALNGIDALGDdQVQVTFKAVPFADWLKWTVAMQ-LQRVRFEKGRIEALp--------- 146 Nitrosospira m...
Q0K5X1        119 GD---ALTQALQDSLGQHGL--KATRLAAGADnSVQVQLDKVPFGAVSGWLQDVRqQQRMKVIDARIVYVg--------- 184 Cupriavidus ne...
Q1LHW4        104 GD---ALTQALQDSLVQHGL--KATRLMTTGDnAVQIQLDKVPFGSVAGWLQDVRlQQRLKVTDTRISYVg--------- 169 Cupriavidus me...
Q13SJ8         86 GA---ALKDALTASLNDHGL--AATQIQVIGN-AVQIQLKNASFPAWTTWVDDVRkQFKVQVLEAHATALk--------- 150 Paraburkholder...
Q9I5P1         98 GT---ADAEAIRRSLRDQGL--DGFQLDAPQPgQWQLDFASVSGEALLRWLARSPaALRLSVSEAQVTRLdapseersgs 172 Pseudomonas ae...
Q9ABP4         78 GA---APQAVVEAAASRVGL--PIARHRQDANgRFTIWIAAIDSKILLPWTAGLErEGAVKVTDFTASRL---------- 142 Caulobacter vi...
WP_012133069   80 TN---NPRTVIEESAKEIHL--ALSDIRQDER-SLSFVVEQVNIYELKNWLREVNvTSGVQLQKMDLRPVd--------- 144 Citrobacter
WP_011815172  160 ----EDGLVNVRLTL-EVG 173 Halorhodospira halophila
jgi:Mpe_A3134 153 ----PNGYSGSVLLTlPRP 167
jgi:Swit_2585 156 ----SSGFVSAELMV---R 167
Q2Y7T4        147 ----EPGIVTVTGTFvRAT 161 Nitrosospira multiformis ATCC 25196
Q0K5X1        185 ----ATALVNVSATLqGPG 199 Cupriavidus necator H16
Q1LHW4        170 ----ATALVNMTATLqGPG 184 Cupriavidus metallidurans CH34
Q13SJ8        151 ----EDGQVDLTASLqPst 165 Paraburkholderia xenovorans LB400
Q9I5P1        173 snelSGGLVSASIHLqSTs 191 Pseudomonas aeruginosa
Q9ABP4        143 ----DNGLIEAEITFaRAA 157 Caulobacter vibrioides
WP_012133069  145 ----RQSDVKANITLsWNK 159 Citrobacter
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