Conserved Protein Domain Family
T2SSM

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pfam04612: T2SSM 
Type II secretion system (T2SS), protein M
This family of membrane proteins consists of Type II secretion system protein M sequences from several Gram-negative (diderm) bacteria. The precise function of these proteins is unknown, though in Vibrio cholerae, the T2SM (EpsM) protein interacts with the T2SL (EpsL) protein, and also forms homodimers.
Statistics
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PSSM-Id: 377391
View PSSM: pfam04612
Aligned: 35 rows
Threshold Bit Score: 69.6312
Threshold Setting Gi: 123655835
Created: 5-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Hhal_2387    10 RAEAERFWSARNPRERWLLGSGGLLVLVVVPYVAVWEPLTERRDQLQAQVAEQRQDLAWMRSAAEEIHah-dgDNGSAEP 88  Halorhodospi...
wugsc:CKO_02219   5 IAQLKARYQNYSDRERGLITLCAAAMCCAVIYYGGIIPLDHMIQNSQSTLMRQKETLRWMRDEIDKNH-----LQAKVLK 79  Citrobacter ...
Q31J18            7 KQTALQIWKGFSQRDQRAIMILGGVLLCAVLYFLIWLPSEHAKQQAQQKLALSQQKWDWLNEQLPKVAqrgpvLPASTLK 86  Hydrogenovib...
wugsc:KPN_00151   1 MANLLIWWRQRTPSEQRLLLGLTGLLAACAFWYGLWQPWRAREAQWRQTLVKEQASLRWMTEQAPRLQql-sqQPAPAAK 79  Klebsiella p...
jgi:Rpic_3397    26 rDAATTFWMQREPRERRILAGGGVVLLLVIVYLVLWEPAFEGQRRIEKALPQMRSQLAEMETLGQEARglsaiAAAPVPR 105 Ralstonia pi...
Q0K5X1           40 QERFNAFWSARNPREQAILAGGGALLALVIGYLVLWEPAADGRERLARNLPKLRADLAEMESLAQEARgl-kaTPAPALR 118 Cupriavidus ...
Q1LHW4           25 REQVDVFWTARNPREQAILGGGAVVLVLVFGYLLLWEPASVEGARLMRNLPVLRADLAEMETLAQEARgl-saNRAPSLR 103 Cupriavidus ...
jgi:Mpe_A3134    13 SEQWRARWRRMARRERRLITAAAIVVGVALVWMLGVQPAWRSLRDTPAQIDAVEFQLQQMQRQAAEARel-rkLPTVKPA 91  Methylibium ...
Q4KD21           17 RAQALGHWNGLALREKRLLGATALGLLGLLLWLLLIQPPLKKIDYWQAETPKLRSQAEALEVLLHEVAagsrnAPGE--- 93  Pseudomonas ...
Q9I5P1           22 llRLQAYWRQLAPRERKILAGGGLALCLALTWQVFVDPPLARIEHWQAELPRLRAQAAAVDGVLREVEal----rGPTLS 97  Pseudomonas ...
jgi:Hhal_2387    89 VTderSLLSLVDRAAREAGId--dQLSRVQPDGDgTLRVWMDRVPFDELMNWLDGLQRAAGVEVDALTVERTQ------- 159 Halorhodospi...
wugsc:CKO_02219  80 TN---NPRTVIEESAKEIHL----ALSDIRQDER-SLSFVVEQVNIYELKNWLREVNVTSGVQLQKMDLRPVD------- 144 Citrobacter ...
Q31J18           87 TTe--GLMQFIQAQLRQLNLy--qTIERIETQGH-KVVVEFKEVNAPRLFRWLSQQE-QQGLIAYSADLKPL-------- 152 Hydrogenovib...
wugsc:KPN_00151  80 E----ALTALVMREAASHGL----TVIRLQPQGK-RLQITLQHCAFQALIDWLDAPA-MRGVNAISLSVTGQPs------ 143 Klebsiella p...
jgi:Rpic_3397   106 GA---ELQQALNTSLTNHGL----KATRMAMSGE-SVQVQLDKVPFGAVAEWLQEVRQAQRMKVIDTNIKYVG------- 170 Ralstonia pi...
Q0K5X1          119 GD---ALTQALQDSLGQHGL----KATRLAAGADnSVQVQLDKVPFGAVSGWLQDVRQQQRMKVIDARIVYVG------- 184 Cupriavidus ...
Q1LHW4          104 GD---ALTQALQDSLVQHGL----KATRLMTTGDnAVQIQLDKVPFGSVAGWLQDVRLQQRLKVTDTRISYVG------- 169 Cupriavidus ...
jgi:Mpe_A3134    92 QA-----EAALRGATERLG-----TNARLTLQGD-RATLTLSGVPGEALAAWLGEVRSAARARPDEAKLSHG-------- 152 Methylibium ...
Q4KD21           94 -----SLEQALRQALDAAGLqgryQLQHADQAGPeSWRLTFEQAPADAVVGWLLGAPRQFSLQVVEARLQRADaaa---- 164 Pseudomonas ...
Q9I5P1           98 GT---ADAEAIRRSLRDQGL----DGFQLDAPQPgQWQLDFASVSGEALLRWLARSPAALRLSVSEAQVTRLDapseers 170 Pseudomonas ...
jgi:Hhal_2387   160 ------EDGLVNVRLTL--EVG 173 Halorhodospira halophila SL1
wugsc:CKO_02219 145 ------RQSDVKANITLs-WNK 159 Citrobacter koseri ATCC BAA-895
Q31J18          153 ------QPGIVTAKVIF--EVS 166 Hydrogenovibrio crunogenus XCL-2
wugsc:KPN_00151 144 ------RPGWVTVNHLLl-ERD 158 Klebsiella pneumoniae subsp. pneumoniae MGH 78578
jgi:Rpic_3397   171 ------ATALVNVTATLq-Gpa 185 Ralstonia pickettii 12J
Q0K5X1          185 ------ATALVNVSATLq-GPG 199 Cupriavidus necator H16
Q1LHW4          170 ------ATALVNMTATLq-GPG 184 Cupriavidus metallidurans CH34
jgi:Mpe_A3134   153 ------PNGYSGSVLLTl-PRP 167 Methylibium petroleiphilum PM1
Q4KD21          165 ---aqdSAGTLSGTVRMdqAQG 183 Pseudomonas protegens Pf-5
Q9I5P1          171 gssnelSGGLVSASIHLq-STs 191 Pseudomonas aeruginosa
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