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IGF2BP2 insulin like growth factor 2 mRNA binding protein 2 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100344927, updated on 3-Apr-2024

Summary

Gene symbol
IGF2BP2
Gene description
insulin like growth factor 2 mRNA binding protein 2
See related
Ensembl:ENSOCUG00000005057
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
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Genomic context

Location:
chromosome: 14
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 14 NC_067387.1 (80919393..81090400)

Chromosome 14 - NC_067387.1Genomic Context describing neighboring genes Neighboring gene nmrA-like family domain-containing protein 1 Neighboring gene chromobox protein homolog 1-like Neighboring gene transformer 2 beta homolog Neighboring gene uncharacterized LOC127482906 Neighboring gene SUMO specific peptidase 2 Neighboring gene lipase H Neighboring gene transmembrane protein 41A

Genomic regions, transcripts, and products

Genomic Sequence:
NC_067387.1 Chromosome 14 Reference UM_NZW_1.0 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mRNA 3'-UTR binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of gene expression IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
insulin-like growth factor 2 mRNA-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067387.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    80919393..81090400
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_051818834.1XP_051674794.1  insulin-like growth factor 2 mRNA-binding protein 2 isoform X2

  2. XM_002716463.4XP_002716509.1  insulin-like growth factor 2 mRNA-binding protein 2 isoform X1

    UniProtKB/TrEMBL
    G1SN43
    Related
    ENSOCUP00000004380.3
    Conserved Domains (4) summary
    cd00105
    Location:277342
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:430493
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
    cd12626
    Location:278
    RRM1_IGF2BP2; RNA recognition motif 1 in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)
    cd12629
    Location:82157
    RRM2_IGF2BP2; RNA recognition motif 2 in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)
  3. XM_002716464.4XP_002716510.1  insulin-like growth factor 2 mRNA-binding protein 2 isoform X3

    UniProtKB/TrEMBL
    G1SN43
    Related
    ENSOCUP00000036643.1
    Conserved Domains (4) summary
    cd00105
    Location:277342
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:387450
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
    cd12626
    Location:278
    RRM1_IGF2BP2; RNA recognition motif 1 in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)
    cd12629
    Location:82157
    RRM2_IGF2BP2; RNA recognition motif 2 in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)