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    INPPL1 inositol polyphosphate phosphatase like 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 783833, updated on 17-Aug-2024

    Summary

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    Official Symbol
    INPPL1provided by VGNC
    Official Full Name
    inositol polyphosphate phosphatase like 1provided by VGNC
    Primary source
    VGNC:VGNC:30215
    See related
    BGD:BT23401; Ensembl:ENSBTAG00000019167
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 15
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (51827681..51842831)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene folate receptor 2 (fetal) Neighboring gene uncharacterized LOC112441638 Neighboring gene paired like homeobox 2A Neighboring gene caseinolytic mitochondrial matrix peptidase chaperone subunit B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphatidylinositol dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
    NP_001178105.1
    XP_024831340.1
    XP_059730989.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191176.2 → NP_001178105.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

      See identical proteins and their annotated locations for NP_001178105.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000015
      UniProtKB/TrEMBL
      E1BBJ7
      Related
      ENSBTAP00000025510.5, ENSBTAT00000025510.7
      Conserved Domains (4) summary
      cd09491
      Location:1201 → 1262
      SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins
      cd09101
      Location:430 → 733
      INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins
      cd10343
      Location:22 → 124
      SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)
      cl26464
      Location:108 → 180
      Atrophin-1; Atrophin-1 family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      51827681..51842831
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059875006.1 → XP_059730989.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1

      UniProtKB/TrEMBL
      E1BBJ7

    2. XM_024975572.2 → XP_024831340.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1

      UniProtKB/TrEMBL
      E1BBJ7
      Conserved Domains (4) summary
      cd09491
      Location:1201 → 1262
      SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins
      cd09101
      Location:430 → 733
      INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins
      cd10343
      Location:22 → 124
      SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)
      cl26464
      Location:108 → 180
      Atrophin-1; Atrophin-1 family
    Nucleotide Protein Strain
    Heading Accession and Version

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