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    MAP3K6 mitogen-activated protein kinase kinase kinase 6 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 456674, updated on 29-Mar-2024

    Summary

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    Official Symbol
    MAP3K6provided by VGNC
    Official Full Name
    mitogen-activated protein kinase kinase kinase 6provided by VGNC
    Primary source
    VGNC:VGNC:8073
    Locus tag
    CK820_G0045787
    See related
    Ensembl:ENSPTRG00000000404
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (203625150..203636660)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (27662634..27674066, complement)

    Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 3 Neighboring gene CD164 molecule like 2 Neighboring gene ficolin 3 Neighboring gene synaptotagmin like 1 Neighboring gene transmembrane protein 222 Neighboring gene actin, alpha skeletal muscle-like Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables MAP kinase kinase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase kinase kinase 6
    XP_024213033.1
    XP_024213034.1
    XP_024213035.1
    XP_024213038.1
    XP_054520473.1
    XP_513244.4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      203625150..203636660
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054664498.2 → XP_054520473.1  mitogen-activated protein kinase kinase kinase 6 isoform X5

    2. XM_024357266.3 → XP_024213034.1  mitogen-activated protein kinase kinase kinase 6 isoform X3

      UniProtKB/TrEMBL
      H2PYF3
      Conserved Domains (2) summary
      cd06624
      Location:639 → 906
      STKc_ASK; Catalytic domain of the Serine/Threonine Kinase, Apoptosis signal-regulating kinase
      pfam13281
      Location:129 → 506
      DUF4071; Domain of unknown function (DUF4071)

    3. XM_024357267.3 → XP_024213035.1  mitogen-activated protein kinase kinase kinase 6 isoform X4

      UniProtKB/TrEMBL
      H2PYF3
      Conserved Domains (2) summary
      cd06624
      Location:582 → 849
      STKc_ASK; Catalytic domain of the Serine/Threonine Kinase, Apoptosis signal-regulating kinase
      pfam13281
      Location:129 → 449
      DUF4071; Domain of unknown function (DUF4071)

    4. XM_024357270.3 → XP_024213038.1  mitogen-activated protein kinase kinase kinase 6 isoform X6

      UniProtKB/TrEMBL
      H2PYF3
      Conserved Domains (2) summary
      cd06624
      Location:401 → 668
      STKc_ASK; Catalytic domain of the Serine/Threonine Kinase, Apoptosis signal-regulating kinase
      pfam13281
      Location:129 → 288
      DUF4071; Domain of unknown function (DUF4071)

    5. XM_513244.7 → XP_513244.4  mitogen-activated protein kinase kinase kinase 6 isoform X1

      UniProtKB/TrEMBL
      A0A2J8JNY0, A0A803KKN5, H2PYF3, K7B4W9
      Conserved Domains (3) summary
      cd06624
      Location:639 → 906
      STKc_ASK; Catalytic domain of the Serine/Threonine Kinase, Apoptosis signal-regulating kinase
      pfam13281
      Location:129 → 507
      DUF4071; Domain of unknown function (DUF4071)
      pfam19039
      Location:523 → 616
      ASK_PH; ASK kinase PH domain

    6. XM_024357265.3 → XP_024213033.1  mitogen-activated protein kinase kinase kinase 6 isoform X2

      UniProtKB/TrEMBL
      A0A2J8JP03, H2PYF3
      Conserved Domains (3) summary
      cd06624
      Location:631 → 898
      STKc_ASK; Catalytic domain of the Serine/Threonine Kinase, Apoptosis signal-regulating kinase
      pfam13281
      Location:129 → 499
      DUF4071; Domain of unknown function (DUF4071)
      pfam19039
      Location:515 → 608
      ASK_PH; ASK kinase PH domain
    Nucleotide Protein
    Heading Accession and Version

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