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    slf1 SMC5-SMC6 complex localization factor 1 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100495961, updated on 8-Mar-2024

    Summary

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    Official Symbol
    slf1provided by Xenbase
    Official Full Name
    SMC5-SMC6 complex localization factor 1provided by Xenbase
    Primary source
    Xenbase:XB-GENE-983324
    See related
    Ensembl:ENSXETG00000013387
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    ankrd32
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 1 NC_030677.2 (177638092..177678943, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 1 NC_030677.1 (172062436..172103645)

    Chromosome 1 - NC_030677.2Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 81 member B Neighboring gene multiple C2 domains, transmembrane 1 Neighboring gene uncharacterized LOC116407661 Neighboring gene KIAA0825 Neighboring gene ARB2 cotranscriptional regulator A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Process Evidence Code Pubs
    involved_in DNA damage response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within positive regulation of double-strand break repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein localization to site of double-strand break IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in site of double-strand break IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SMC5-SMC6 complex localization factor protein 1
    Names
    ankyrin repeat domain 32

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030677.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      177638092..177678943 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018090793.2 → XP_017946282.1  SMC5-SMC6 complex localization factor protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A803JSH8, A0A8J0SQZ9

    2. XM_012968376.3 → XP_012823830.1  SMC5-SMC6 complex localization factor protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A803JSH8, A0A8J0SKV8
      Conserved Domains (4) summary
      cd00204
      Location:655 → 784
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:663 → 750
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:659 → 690
      ANK; ANK repeat [structural motif]
      cl00038
      Location:16 → 67
      BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...

    3. XM_002933423.5 → XP_002933469.2  SMC5-SMC6 complex localization factor protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A803JSH8, F6V0Z8
      Related
      ENSXETP00000029347.4, ENSXETT00000029347.5
      Conserved Domains (4) summary
      COG0666
      Location:598 → 780
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:658 → 689
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:662 → 749
      Ank_2; Ankyrin repeats (3 copies)
      cl00038
      Location:12 → 92
      BRCT; C-terminal domain of the breast cancer suppressor protein (BRCA1) and related domains
    Nucleotide Protein Strain
    Heading Accession and Version

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