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    anp32e acidic (leucine-rich) nuclear phosphoprotein 32 family, member E [ Danio rerio (zebrafish) ]

    Gene ID: 406562, updated on 27-Mar-2024

    Summary

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    Official Symbol
    anp32eprovided by ZNC
    Official Full Name
    acidic (leucine-rich) nuclear phosphoprotein 32 family, member Eprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2448
    See related
    Ensembl:ENSDARG00000054804 AllianceGenome:ZFIN:ZDB-GENE-040426-2448
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:65995; zgc:85827; wu:fb22e03; wu:fc04c12; wu:fc19a08; wu:fc79f04; wu:fi39c10
    Summary
    Predicted to enable histone binding activity and phosphatase inhibitor activity. Predicted to be involved in histone exchange and regulation of apoptotic process. Predicted to act upstream of or within chromatin organization. Predicted to be located in cytoplasm. Predicted to be part of Swr1 complex. Predicted to be active in nucleus. Orthologous to human ANP32E (acidic nuclear phosphoprotein 32 family member E). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See anp32e in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (42328442..42341815)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (42759005..42772378)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene si:ch211-191i18.2 Neighboring gene cocaine- and amphetamine-regulated transcript 4 Neighboring gene pleckstrin homology domain containing, family O member 1a Neighboring gene vacuolar protein sorting 45 homolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Quantitative proteomics analysis of zebrafish exposed to sub-lethal dosages of β-methyl-amino-L-alanine (BMAA). Frøyset AK, et al. Sci Rep, 2016 Jul 12. PMID 27404450, Free PMC Article
    2. Placeholder Nucleosomes Underlie Germline-to-Embryo DNA Methylation Reprogramming. Murphy PJ, et al. Cell, 2018 Feb 22. PMID 29456083
    3. Identification of nodal signaling targets by array analysis of induced complex probes. Dickmeis T, et al. Dev Dyn, 2001 Dec. PMID 11748827
    4. The Anp32 family of proteins containing leucine-rich repeats. Matilla A, et al. Cerebellum, 2005. PMID 15895553
    5. Olfactory imprinting is correlated with changes in gene expression in the olfactory epithelia of the zebrafish. Harden MV, et al. J Neurobiol, 2006 Nov. PMID 17013923

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Anp32e protects against accumulation of H2A.Z at Sox motif containing promoters during zebrafish gastrulation.
      Title: Anp32e protects against accumulation of H2A.Z at Sox motif containing promoters during zebrafish gastrulation.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC113940

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables histone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables histone chaperone activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables phosphatase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Swr1 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    acidic leucine-rich nuclear phosphoprotein 32 family member E

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213277.1 → NP_998442.1  acidic leucine-rich nuclear phosphoprotein 32 family member E

      See identical proteins and their annotated locations for NP_998442.1

      Status: PROVISIONAL

      Source sequence(s)
      BC068403
      UniProtKB/Swiss-Prot
      Q6NUW5
      Related
      ENSDARP00000071527.3, ENSDART00000077059.5
      Conserved Domains (3) summary
      sd00031
      Location:44 → 65
      LRR_1; leucine-rich repeat [structural motif]
      pfam12799
      Location:89 → 130
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:64 → 125
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      42328442..42341815
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NUW5.1 GenPept UniProtKB/Swiss-Prot:Q6NUW5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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