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    SCAP SREBF chaperone [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711528, updated on 5-Mar-2024

    Summary

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    Official Symbol
    SCAPprovided by VGNC
    Official Full Name
    SREBF chaperoneprovided by VGNC
    Primary source
    VGNC:VGNC:77140
    See related
    Ensembl:ENSMMUG00000014046
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (103424973..103493571, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (95061540..95103008)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene kinesin family member 9 Neighboring gene kelch like family member 18 Neighboring gene protein tyrosine phosphatase non-receptor type 23 Neighboring gene bolA-like protein 2 pseudogene Neighboring gene elongator acetyltransferase complex subunit 6 Neighboring gene chondroitin sulfate proteoglycan 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sterol binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SREBP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sterol regulatory element-binding protein cleavage-activating protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      103424973..103493571 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028844066.1 → XP_028699899.1  sterol regulatory element-binding protein cleavage-activating protein isoform X2

      UniProtKB/TrEMBL
      F7ANE1, H9FRI8
      Related
      ENSMMUP00000018459.4, ENSMMUT00000019717.4
      Conserved Domains (5) summary
      smart00320
      Location:771 → 802
      WD40; WD40 repeats
      TIGR00917
      Location:11 → 466
      2A060601; Niemann-Pick C type protein family
      sd00039
      Location:958 → 1004
      7WD40; WD40 repeat [structural motif]
      pfam12349
      Location:308 → 452
      Sterol-sensing; Sterol-sensing domain of SREBP cleavage-activation
      cl29593
      Location:1077 → 1234
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. XM_028844065.1 → XP_028699898.1  sterol regulatory element-binding protein cleavage-activating protein isoform X1

      UniProtKB/TrEMBL
      F7AH97, H9FRI8
      Related
      ENSMMUP00000018460.4, ENSMMUT00000019718.4
      Conserved Domains (5) summary
      smart00320
      Location:771 → 802
      WD40; WD40 repeats
      TIGR00917
      Location:11 → 466
      2A060601; Niemann-Pick C type protein family
      sd00039
      Location:959 → 1005
      7WD40; WD40 repeat [structural motif]
      pfam12349
      Location:308 → 452
      Sterol-sensing; Sterol-sensing domain of SREBP cleavage-activation
      cl29593
      Location:1078 → 1235
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. XM_015131089.2 → XP_014986575.2  sterol regulatory element-binding protein cleavage-activating protein isoform X1

      UniProtKB/TrEMBL
      F7AH97, H9FRI8
      Conserved Domains (5) summary
      smart00320
      Location:771 → 802
      WD40; WD40 repeats
      TIGR00917
      Location:11 → 466
      2A060601; Niemann-Pick C type protein family
      sd00039
      Location:959 → 1005
      7WD40; WD40 repeat [structural motif]
      pfam12349
      Location:308 → 452
      Sterol-sensing; Sterol-sensing domain of SREBP cleavage-activation
      cl29593
      Location:1078 → 1235
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    4. XM_015131090.2 → XP_014986576.2  sterol regulatory element-binding protein cleavage-activating protein isoform X1

      UniProtKB/TrEMBL
      F7AH97, H9FRI8
      Conserved Domains (5) summary
      smart00320
      Location:771 → 802
      WD40; WD40 repeats
      TIGR00917
      Location:11 → 466
      2A060601; Niemann-Pick C type protein family
      sd00039
      Location:959 → 1005
      7WD40; WD40 repeat [structural motif]
      pfam12349
      Location:308 → 452
      Sterol-sensing; Sterol-sensing domain of SREBP cleavage-activation
      cl29593
      Location:1078 → 1235
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    5. XM_028844067.1 → XP_028699900.1  sterol regulatory element-binding protein cleavage-activating protein isoform X3

      UniProtKB/TrEMBL
      H9FRI8
      Conserved Domains (4) summary
      smart00320
      Location:541 → 572
      WD40; WD40 repeats
      sd00039
      Location:729 → 775
      7WD40; WD40 repeat [structural motif]
      pfam12349
      Location:78 → 222
      Sterol-sensing; Sterol-sensing domain of SREBP cleavage-activation
      cl29593
      Location:848 → 1005
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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