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    SPHK2 sphingosine kinase 2 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 468943, updated on 3-Apr-2024

    Summary

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    Official Symbol
    SPHK2provided by VGNC
    Official Full Name
    sphingosine kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:13534
    Locus tag
    CK820_G0042310
    See related
    Ensembl:ENSPTRG00000011246
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 19
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 20 NC_072418.2 (51563380..51574024)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 19 NC_072417.1 (51563413..51574051)

    Chromosome 20 - NC_072418.2Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 83 member E Neighboring gene sperm acrosome associated 4 Neighboring gene ribosomal protein L18 Neighboring gene D-box binding PAR bZIP transcription factor Neighboring gene carbonic anhydrase 11

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables D-erythro-sphingosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphinganine-1-phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphingosine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sphingosine kinase 2
    XP_016791920.2
    XP_016791921.2
    XP_016791923.2
    XP_016791925.2
    XP_016791926.2
    XP_016791927.2
    XP_024207290.1
    XP_024207292.1
    XP_063658106.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072418.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      51563380..51574024
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_016936432.4 → XP_016791921.2  sphingosine kinase 2 isoform X2

      UniProtKB/TrEMBL
      A0A2J8K255, A0A803KKM7, K7B2G6, K7BHM6
      Conserved Domains (2) summary
      cl25836
      Location:380 → 504
      Retinal; Retinal protein
      cl27661
      Location:187 → 381
      LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]

    2. XM_024351522.3 → XP_024207290.1  sphingosine kinase 2 isoform X4

      UniProtKB/TrEMBL
      A0A2J8K277, K7BHM6
      Conserved Domains (2) summary
      cl25836
      Location:321 → 445
      Retinal; Retinal protein
      cl27661
      Location:128 → 322
      LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]

    3. XM_063802036.1 → XP_063658106.1  sphingosine kinase 2 isoform X5

      UniProtKB/TrEMBL
      A0A2J8K249

    4. XM_016936438.4 → XP_016791927.2  sphingosine kinase 2 isoform X3

      UniProtKB/TrEMBL
      A0A2J8K267, K7BHM6
      Conserved Domains (2) summary
      cl25836
      Location:344 → 468
      Retinal; Retinal protein
      cl27661
      Location:151 → 345
      LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]

    5. XM_016936434.4 → XP_016791923.2  sphingosine kinase 2 isoform X3

      UniProtKB/TrEMBL
      A0A2J8K267, K7BHM6
      Conserved Domains (2) summary
      cl25836
      Location:344 → 468
      Retinal; Retinal protein
      cl27661
      Location:151 → 345
      LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]

    6. XM_024351524.3 → XP_024207292.1  sphingosine kinase 2 isoform X5

      UniProtKB/TrEMBL
      A0A2J8K249
      Conserved Domains (2) summary
      cl25836
      Location:174 → 298
      Retinal; Retinal protein
      cl27661
      Location:1 → 175
      LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]

    7. XM_016936437.4 → XP_016791926.2  sphingosine kinase 2 isoform X3

      UniProtKB/TrEMBL
      A0A2J8K267, K7BHM6
      Conserved Domains (2) summary
      cl25836
      Location:344 → 468
      Retinal; Retinal protein
      cl27661
      Location:151 → 345
      LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]

    8. XM_016936436.4 → XP_016791925.2  sphingosine kinase 2 isoform X3

      UniProtKB/TrEMBL
      A0A2J8K267, K7BHM6
      Conserved Domains (2) summary
      cl25836
      Location:344 → 468
      Retinal; Retinal protein
      cl27661
      Location:151 → 345
      LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]

    9. XM_016936431.4 → XP_016791920.2  sphingosine kinase 2 isoform X1

      UniProtKB/TrEMBL
      K7BHM6
      Conserved Domains (2) summary
      cl25836
      Location:442 → 566
      Retinal; Retinal protein
      cl27661
      Location:249 → 443
      LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
    Nucleotide Protein
    Heading Accession and Version

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