RNH1 ribonuclease/angiogenin inhibitor 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: RNH1provided by CGNC
Full Name: ribonuclease/angiogenin inhibitor 1provided by CGNC
Primary source: CGNC:5211
See related: Ensembl:ENSGALG00010025610
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	5	NC_052536.1 (15712878..15721815)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	5	NC_052577.1 (15687425..15696151)

Chromosome 5 - NC_052536.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

X-ray crystallographic analysis of RNH1 from mouse, bovine and chicken binding to RNase reveals two residues that appear to contribute to the differential binding affinity.
Title: Functional evolution of ribonuclease inhibitor: insights from birds and reptiles.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ribonuclease inhibitor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001006473.2 → NP_001006473.2 ribonuclease inhibitor

Status: PROVISIONAL

Source sequence(s)

JAENSK010000214

UniProtKB/TrEMBL

Q5ZIY8

Related

ENSGALP00010038644.1, ENSGALT00010062494.1

Conserved Domains (3) summary

cd00116
Location:1 → 318

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

sd00033
Location:53 → 81

LRR_RI; leucine-rich repeat [structural motif]

cl39015
Location:309 → 429

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

15712878..15721815

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015286775.4 → XP_015142261.3 ribonuclease inhibitor isoform X2

UniProtKB/TrEMBL

Q5ZIY8
XM_040700871.2 → XP_040556805.1 ribonuclease inhibitor isoform X1

UniProtKB/TrEMBL

Q5ZIY8

Conserved Domains (3) summary

cd00116
Location:67 → 384

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

sd00033
Location:119 → 147

LRR_RI; leucine-rich repeat [structural motif]

cl39015
Location:375 → 519

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

15687425..15696151

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046918260.1 → XP_046774216.1 ribonuclease inhibitor isoform X3

UniProtKB/TrEMBL

Q5ZIY8
XM_046918261.1 → XP_046774217.1 ribonuclease inhibitor isoform X1

UniProtKB/TrEMBL

Q5ZIY8