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    IGF2BP2 insulin like growth factor 2 mRNA binding protein 2 [ Bos taurus (cattle) ]

    Gene ID: 519028, updated on 5-Mar-2024

    Summary

    Official Symbol
    IGF2BP2provided by VGNC
    Official Full Name
    insulin like growth factor 2 mRNA binding protein 2provided by VGNC
    Primary source
    VGNC:VGNC:30080
    See related
    BGD:BT26513; Ensembl:ENSBTAG00000007666
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
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    Genomic context

    Location:
    chromosome: 1
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (81402074..81573565)

    Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene transformer 2 beta homolog Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene SUMO specific peptidase 2 Neighboring gene lipase H

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mRNA 3'-UTR binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    insulin-like growth factor 2 mRNA-binding protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192504.2NP_001179433.1  insulin-like growth factor 2 mRNA-binding protein 2

      See identical proteins and their annotated locations for NP_001179433.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000001
      UniProtKB/TrEMBL
      A0A3Q1NG08, E1BFI4
      Related
      ENSBTAP00000094263.1, ENSBTAT00000130440.1
      Conserved Domains (5) summary
      cd00105
      Location:277342
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:430493
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      cd12626
      Location:278
      RRM1_IGF2BP2; RNA recognition motif 1 in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)
      pfam00013
      Location:514577
      KH_1; KH domain
      cl17169
      Location:82157
      RRM_SF; RNA recognition motif (RRM) superfamily

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      81402074..81573565
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005201476.5XP_005201533.1  insulin-like growth factor 2 mRNA-binding protein 2 isoform X1

      See identical proteins and their annotated locations for XP_005201533.1

      UniProtKB/TrEMBL
      A0A3Q1MM04, A0A3Q1NG08
      Related
      ENSBTAP00000072763.1, ENSBTAT00000083817.2
      Conserved Domains (6) summary
      cd12626
      Location:278
      RRM1_IGF2BP2; RNA recognition motif 1 (RRM1) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)
      cd12629
      Location:82157
      RRM2_IGF2BP2; RNA recognition motif 2 (RRM2) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)
      cd22491
      Location:195268
      KH-I_IGF2BP2_rpt1; first type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins
      cd22494
      Location:276352
      KH-I_IGF2BP2_rpt2; second type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins
      cd22497
      Location:383459
      KH-I_IGF2BP2_rpt3; third type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins
      cd22500
      Location:466543
      KH-I_IGF2BP2_rpt4; fourth type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins