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    TGS1 trimethylguanosine synthase 1 [ Bos taurus (cattle) ]

    Gene ID: 511392, updated on 11-Apr-2024

    Summary

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    Official Symbol
    TGS1provided by VGNC
    Official Full Name
    trimethylguanosine synthase 1provided by VGNC
    Primary source
    VGNC:VGNC:35815
    See related
    BGD:BT17013; Ensembl:ENSBTAG00000005898
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See TGS1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 14 NC_037341.1 (23070145..23097443)

    Chromosome 14 - NC_037341.1Genomic Context describing neighboring genes Neighboring gene XK related 4 Neighboring gene transmembrane protein 68 Neighboring gene LYN proto-oncogene, Src family tyrosine kinase Neighboring gene small nucleolar RNA U54 Neighboring gene ribosomal protein S20

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037341.1 Chromosome 14 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA cap trimethylguanosine synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in 7-methylguanosine RNA capping IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in 7-methylguanosine cap hypermethylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    trimethylguanosine synthase
    Names
    trimethylguanosine synthase homolog
    NP_001192627.1
    XP_005215465.1
    XP_010810296.1
    XP_015329920.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205698.1 → NP_001192627.1  trimethylguanosine synthase

      See identical proteins and their annotated locations for NP_001192627.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000014
      UniProtKB/TrEMBL
      F1N1K9
      Conserved Domains (1) summary
      pfam09445
      Location:691 → 842
      Methyltransf_15; RNA cap guanine-N2 methyltransferase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037341.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      23070145..23097443
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005215408.3 → XP_005215465.1  trimethylguanosine synthase isoform X1

      Related
      ENSBTAP00000007749.6, ENSBTAT00000007749.6
      Conserved Domains (2) summary
      pfam09528
      Location:278 → 690
      Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
      pfam09445
      Location:692 → 843
      Methyltransf_15; RNA cap guanine-N2 methyltransferase

    2. XM_010811994.4 → XP_010810296.1  trimethylguanosine synthase isoform X2

      See identical proteins and their annotated locations for XP_010810296.1

      Conserved Domains (2) summary
      pfam09528
      Location:184 → 596
      Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
      pfam09445
      Location:598 → 749
      Methyltransf_15; RNA cap guanine-N2 methyltransferase

    3. XM_015474434.3 → XP_015329920.1  trimethylguanosine synthase isoform X2

      Conserved Domains (2) summary
      pfam09528
      Location:184 → 596
      Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
      pfam09445
      Location:598 → 749
      Methyltransf_15; RNA cap guanine-N2 methyltransferase
    Nucleotide Protein Strain
    Heading Accession and Version

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