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    GRM8 glutamate metabotropic receptor 8 [ Bos taurus (domestic cattle) ]

    Gene ID: 538360, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GRM8provided by VGNC
    Official Full Name
    glutamate metabotropic receptor 8provided by VGNC
    Primary source
    VGNC:VGNC:106761
    See related
    BGD:BT15449; Ensembl:ENSBTAG00000054974
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See GRM8 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (90671110..91519944, complement)

    Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene transfer RNA arginine (anticodon ACG) Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene uncharacterized LOC132345127 Neighboring gene microRNA mir-592 Neighboring gene transfer RNA lysine (anticodon UUU) Neighboring gene zinc finger protein 800

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables group III metabotropic glutamate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled glutamate receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    metabotropic glutamate receptor 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206117.2 → NP_001193046.1  metabotropic glutamate receptor 8

      See identical proteins and their annotated locations for NP_001193046.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000004
      UniProtKB/TrEMBL
      A0A3Q1LJN2
      Related
      ENSBTAP00000056759.1, ENSBTAT00000072365.2
      Conserved Domains (3) summary
      cd15454
      Location:582 → 892
      7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06376
      Location:40 → 504
      PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
      pfam07562
      Location:512 → 562
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      90671110..91519944 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015470567.3 → XP_015326053.1  metabotropic glutamate receptor 8 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LJN2
      Conserved Domains (3) summary
      cd15454
      Location:582 → 892
      7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06376
      Location:40 → 504
      PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
      pfam07562
      Location:512 → 562
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    2. XM_059885684.1 → XP_059741667.1  metabotropic glutamate receptor 8 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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