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    Eif2s1 eukaryotic translation initiation factor 2 subunit alpha [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101723170, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Eif2s1
    Gene description
    eukaryotic translation initiation factor 2 subunit alpha
    Locus tag
    GW7_03714
    See related
    Ensembl:ENSHGLG00000015570
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624734.1 (33624246..33640667, complement)

    NW_004624734.1Genomic Context describing neighboring genes Neighboring gene proliferation-associated protein 2G4 Neighboring gene pleckstrin 2 Neighboring gene ATPase H+ transporting V1 subunit D Neighboring gene eukaryotic translation initiation factor 2 subunit 3, X-linked pseudogene Neighboring gene protein associated with LIN7 1, MAGUK p55 family member

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624734 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ribosome binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of eukaryotic 48S preinitiation complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of eukaryotic translation initiation factor 2 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of eukaryotic translation initiation factor 2B complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of multi-eIF complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    eukaryotic translation initiation factor 2 subunit 1
    Names
    Eukaryotic translation initiation factor 2 subunit 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624734.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      33624246..33640667 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004837369.3 → XP_004837426.2  eukaryotic translation initiation factor 2 subunit 1 isoform X1

      UniProtKB/TrEMBL
      A0A0P6IYT7
      Related
      ENSHGLP00000021799.1, ENSHGLT00000022009.1
      Conserved Domains (3) summary
      cd04452
      Location:18 → 93
      S1_IF2_alpha; S1_IF2_alpha: The alpha subunit of translation Initiation Factor 2, S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. Eukaryotic and archaeal Initiation Factor 2 (e- and aIF2, respectively) ...
      PTZ00248
      Location:8 → 319
      PTZ00248; eukaryotic translation initiation factor 2 subunit 1; Provisional
      pfam07541
      Location:136 → 245
      EIF_2_alpha; Eukaryotic translation initiation factor 2 alpha subunit

    2. XM_004837368.3 → XP_004837425.1  eukaryotic translation initiation factor 2 subunit 1 isoform X2

      See identical proteins and their annotated locations for XP_004837425.1

      UniProtKB/TrEMBL
      G5C7Y2
      Related
      ENSHGLP00000021798.1, ENSHGLT00000022008.1
      Conserved Domains (1) summary
      PTZ00248
      Location:4 → 315
      PTZ00248; eukaryotic translation initiation factor 2 subunit 1; Provisional
    Nucleotide Protein
    Heading Accession and Version

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