The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Reference UM_NZW_1.0 Primary Assembly

Genomic

1. NW_026259153.1 Reference UM_NZW_1.0 Primary Assembly

   Range

   1728709..2005296

   Download

   GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

1. XM_008273491.3 → XP_008271713.2  rap guanine nucleotide exchange factor 2 isoform X1

2. XM_051831661.1 → XP_051687621.1  rap guanine nucleotide exchange factor 2 isoform X3

3. XM_008273492.3 → XP_008271714.2  rap guanine nucleotide exchange factor 2 isoform X2

4. XM_051831662.1 → XP_051687622.1  rap guanine nucleotide exchange factor 2 isoform X4

5. XM_008273493.3 → XP_008271715.1  rap guanine nucleotide exchange factor 2 isoform X5

   See identical proteins and their annotated locations for XP_008271715.1

   UniProtKB/TrEMBL

   A0A5F9CPU8

   Conserved Domains (5) summary

   smart00100
   Location:181 → 296

   cNMP; Cyclic nucleotide-monophosphate binding domain

   smart00229
   Location:312 → 425

   RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif

   cd00155
   Location:758 → 983

   RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

   cd00992
   Location:429 → 509

   PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

   cl00155
   Location:651 → 735

   UBQ; Ubiquitin-like proteins

6. XM_051831663.1 → XP_051687623.1  rap guanine nucleotide exchange factor 2 isoform X7

7. XM_051831664.1 → XP_051687624.1  rap guanine nucleotide exchange factor 2 isoform X8

8. XM_008273496.3 → XP_008271718.1  rap guanine nucleotide exchange factor 2 isoform X6

   UniProtKB/TrEMBL

   A0A5F9CKY3, A0A5F9CPU8

   Related

   ENSOCUP00000034165.1

   Conserved Domains (5) summary

   smart00100
   Location:136 → 251

   cNMP; Cyclic nucleotide-monophosphate binding domain

   smart00229
   Location:267 → 380

   RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif

   cd00155
   Location:713 → 938

   RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

   cd00992
   Location:384 → 464

   PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

   cl00155
   Location:606 → 690

   UBQ; Ubiquitin-like proteins