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    SYDE2 synapse defective Rho GTPase homolog 2 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 456983, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SYDE2provided by VGNC
    Official Full Name
    synapse defective Rho GTPase homolog 2provided by VGNC
    Primary source
    VGNC:VGNC:10421
    Locus tag
    CK820_G0040677
    See related
    Ensembl:ENSPTRG00000000912
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See SYDE2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (145870332..145920102)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (85379183..85428954, complement)

    Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene chromosome 1 C1orf52 homolog Neighboring gene uncharacterized LOC129137234 Neighboring gene uncharacterized LOC134808994 Neighboring gene microRNA mir-4423 Neighboring gene dynein axonemal intermediate chain 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in synaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho GTPase-activating protein SYDE2
    Names
    synapse defective 1, Rho GTPase, homolog 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      145870332..145920102
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_016921720.4 → XP_016777209.1  rho GTPase-activating protein SYDE2 isoform X3

      UniProtKB/TrEMBL
      A0A2J8K8F1, A0A6D2Y526, H2PZB3

    2. XM_016921721.4 → XP_016777210.1  rho GTPase-activating protein SYDE2 isoform X4

      UniProtKB/TrEMBL
      A0A2J8K8F1, A0A6D2Y526, H2PZB3

    3. XM_016921711.4 → XP_016777200.1  rho GTPase-activating protein SYDE2 isoform X1

      UniProtKB/TrEMBL
      A0A2J8K8F1, A0A6D2Y526, H2PZB3

    4. XM_016921719.4 → XP_016777208.1  rho GTPase-activating protein SYDE2 isoform X2

      UniProtKB/TrEMBL
      A0A2J8K8F1, A0A6D2Y526, H2PZB3
      Related
      ENSPTRP00000001574.5
      Conserved Domains (2) summary
      cl02570
      Location:1011 → 1225
      RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...
      cl14603
      Location:876 → 991
      C2; C2 domain
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials