TRAF2 TNF receptor associated factor 2 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: TRAF2provided by VGNC
Official Full Name: TNF receptor associated factor 2provided by VGNC
Primary source: VGNC:VGNC:47763
See related: Ensembl:ENSCAFG00845005186
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 9

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	9	NC_051813.1 (49565899..49592130, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	9	NC_006591.4 (47901455..47927699, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	9	NC_049230.1 (48687986..48714231, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	9	NC_049269.1 (48342106..48368330, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	9	NC_049750.1 (48640817..48667045, complement)

Chromosome 9 - NC_051813.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables tumor necrosis factor receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ubiquitin protein ligase binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ubiquitin-protein transferase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in activation of NF-kappaB-inducing kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of JNK cascade	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of NF-kappaB transcription factor activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of canonical NF-kappaB signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein K63-linked ubiquitination	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein autoubiquitination	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in tumor necrosis factor-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasmic side of plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
part_of plasma membrane signaling receptor complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: TNF receptor-associated factor 2

XP_005625129.1

EC 2.3.2.27

XP_005625130.1

EC 2.3.2.27

XP_005625131.1

EC 2.3.2.27

XP_022279256.1

EC 2.3.2.27

XP_038342771.1

EC 2.3.2.27

XP_038342772.1

EC 2.3.2.27

XP_038342773.1

EC 2.3.2.27

XP_038342774.1

EC 2.3.2.27

XP_038342775.1

EC 2.3.2.27

XP_038404638.1

EC 2.3.2.27

XP_038404639.1

EC 2.3.2.27

XP_038404640.1

EC 2.3.2.27

XP_038404641.1

EC 2.3.2.27

XP_038404642.1

EC 2.3.2.27

XP_038468573.1

EC 2.3.2.27

XP_038468574.1

EC 2.3.2.27

XP_038468575.1

EC 2.3.2.27

XP_038468576.1

EC 2.3.2.27

XP_038468577.1

EC 2.3.2.27

XP_038470507.1

EC 2.3.2.27

XP_038533860.1

EC 2.3.2.27

XP_038533861.1

EC 2.3.2.27

XP_038533862.1

EC 2.3.2.27

XP_038533863.1

EC 2.3.2.27

XP_038533864.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051813.1 Reference ROS_Cfam_1.0

Range

49565899..49592130 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038677935.1 → XP_038533863.1 TNF receptor-associated factor 2 isoform X2

UniProtKB/TrEMBL

A0A8C0JPC9, A0A8C0MD65, A0A8C0MGX5, A0A8I3MQC7

Conserved Domains (4) summary

cd03778
Location:356 → 519

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 351

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038677933.1 → XP_038533861.1 TNF receptor-associated factor 2 isoform X2

UniProtKB/TrEMBL

A0A8C0JPC9, A0A8C0MD65, A0A8C0MGX5, A0A8I3MQC7

Related

ENSCAFP00845007298.1, ENSCAFT00845009283.1

Conserved Domains (4) summary

cd03778
Location:356 → 519

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 351

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038677934.1 → XP_038533862.1 TNF receptor-associated factor 2 isoform X2

UniProtKB/TrEMBL

A0A8C0JPC9, A0A8C0MD65, A0A8C0MGX5, A0A8I3MQC7

Conserved Domains (4) summary

cd03778
Location:356 → 519

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 351

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038677936.1 → XP_038533864.1 TNF receptor-associated factor 2 isoform X3

UniProtKB/TrEMBL

A0A8C0MGS3, A0A8C0MGX5

Conserved Domains (4) summary

cd03778
Location:302 → 465

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:124 → 181

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:237 → 297

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038677932.1 → XP_038533860.1 TNF receptor-associated factor 2 isoform X1

UniProtKB/TrEMBL

A0A8C0MGX5

Conserved Domains (4) summary

cd03778
Location:354 → 517

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 349

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

Alternate UMICH_Zoey_3.1

Genomic

NC_049269.1 Alternate UMICH_Zoey_3.1

Range

48342106..48368330 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038486846.1 → XP_038342774.1 TNF receptor-associated factor 2 isoform X2

Conserved Domains (4) summary

cd03778
Location:356 → 519

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 351

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038486844.1 → XP_038342772.1 TNF receptor-associated factor 2 isoform X2

Conserved Domains (4) summary

cd03778
Location:356 → 519

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 351

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038486845.1 → XP_038342773.1 TNF receptor-associated factor 2 isoform X2

Conserved Domains (4) summary

cd03778
Location:356 → 519

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 351

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038486847.1 → XP_038342775.1 TNF receptor-associated factor 2 isoform X3

Conserved Domains (4) summary

cd03778
Location:302 → 465

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:124 → 181

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:237 → 297

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038486843.1 → XP_038342771.1 TNF receptor-associated factor 2 isoform X1

Conserved Domains (4) summary

cd03778
Location:354 → 517

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 349

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049750.1 Alternate UNSW_CanFamBas_1.0

Range

48640817..48667045 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038612648.1 → XP_038468576.1 TNF receptor-associated factor 2 isoform X2

Conserved Domains (4) summary

cd03778
Location:356 → 519

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 351

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038612646.1 → XP_038468574.1 TNF receptor-associated factor 2 isoform X2

Conserved Domains (4) summary

cd03778
Location:356 → 519

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 351

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038612647.1 → XP_038468575.1 TNF receptor-associated factor 2 isoform X2

Conserved Domains (4) summary

cd03778
Location:356 → 519

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 351

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038612649.1 → XP_038468577.1 TNF receptor-associated factor 2 isoform X3

Conserved Domains (4) summary

cd03778
Location:302 → 465

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:124 → 181

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:237 → 297

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038612645.1 → XP_038468573.1 TNF receptor-associated factor 2 isoform X1

Conserved Domains (4) summary

cd03778
Location:354 → 517

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 349

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049230.1 Alternate UU_Cfam_GSD_1.0

Range

48687986..48714231 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038548713.1 → XP_038404641.1 TNF receptor-associated factor 2 isoform X2

UniProtKB/TrEMBL

A0A8C0JPC9, A0A8C0MD65, A0A8C0MGX5, A0A8I3MQC7

Conserved Domains (4) summary

cd03778
Location:356 → 519

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 351

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038548711.1 → XP_038404639.1 TNF receptor-associated factor 2 isoform X2

UniProtKB/TrEMBL

A0A8C0JPC9, A0A8C0MD65, A0A8C0MGX5, A0A8I3MQC7

Conserved Domains (4) summary

cd03778
Location:356 → 519

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 351

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038548712.1 → XP_038404640.1 TNF receptor-associated factor 2 isoform X2

UniProtKB/TrEMBL

A0A8C0JPC9, A0A8C0MD65, A0A8C0MGX5, A0A8I3MQC7

Conserved Domains (4) summary

cd03778
Location:356 → 519

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 351

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038548714.1 → XP_038404642.1 TNF receptor-associated factor 2 isoform X3

UniProtKB/TrEMBL

A0A8C0MGS3, A0A8C0MGX5

Conserved Domains (4) summary

cd03778
Location:302 → 465

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:124 → 181

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:237 → 297

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038548710.1 → XP_038404638.1 TNF receptor-associated factor 2 isoform X1

UniProtKB/TrEMBL

A0A8C0MGX5

Conserved Domains (4) summary

cd03778
Location:354 → 517

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 349

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

47901455..47927699 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005625074.4 → XP_005625131.1 TNF receptor-associated factor 2 isoform X2

See identical proteins and their annotated locations for XP_005625131.1

UniProtKB/TrEMBL

A0A8C0JPC9, A0A8C0MD65, A0A8C0MGX5, A0A8I3MQC7

Conserved Domains (4) summary

cd03778
Location:356 → 519

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 351

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_005625072.3 → XP_005625129.1 TNF receptor-associated factor 2 isoform X2

See identical proteins and their annotated locations for XP_005625129.1

UniProtKB/TrEMBL

A0A8C0JPC9, A0A8C0MD65, A0A8C0MGX5, A0A8I3MQC7

Conserved Domains (4) summary

cd03778
Location:356 → 519

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 351

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_005625073.4 → XP_005625130.1 TNF receptor-associated factor 2 isoform X2

See identical proteins and their annotated locations for XP_005625130.1

UniProtKB/TrEMBL

A0A8C0JPC9, A0A8C0MD65, A0A8C0MGX5, A0A8I3MQC7

Conserved Domains (4) summary

cd03778
Location:356 → 519

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 351

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_038614579.1 → XP_038470507.1 TNF receptor-associated factor 2 isoform X3

UniProtKB/TrEMBL

A0A8C0MGS3, A0A8C0MGX5

Conserved Domains (4) summary

cd03778
Location:302 → 465

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:124 → 181

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:237 → 297

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
XM_022423548.2 → XP_022279256.1 TNF receptor-associated factor 2 isoform X1

UniProtKB/TrEMBL

A0A8C0MGX5

Conserved Domains (4) summary

cd03778
Location:354 → 517

MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...

pfam02176
Location:178 → 235

zf-TRAF; TRAF-type zinc finger

cd16639
Location:32 → 73

RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

pfam16673
Location:291 → 349

TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain