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    apbb1ip amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein [ Danio rerio (zebrafish) ]

    Gene ID: 393607, updated on 27-Mar-2024

    Summary

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    Official Symbol
    apbb1ipprovided by ZNC
    Official Full Name
    amyloid beta (A4) precursor protein-binding, family B, member 1 interacting proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1318
    See related
    Ensembl:ENSDARG00000016505 AllianceGenome:ZFIN:ZDB-GENE-040426-1318
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:63968
    Summary
    Predicted to act upstream of or within signal transduction. Predicted to be located in cytoplasm; cytoskeleton; and membrane. Predicted to be active in cytosol and plasma membrane. Is expressed in atrioventricular canal; cardiac ventricle; and presumptive cardiac ventricle heart tube. Orthologous to human APBB1IP (amyloid beta precursor protein binding family B member 1 interacting protein). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 24
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (6040033..6078200, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (6010704..6048871, complement)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene tripartite motif-containing protein 16-like Neighboring gene finTRIM family, member 61 Neighboring gene uncharacterized LOC101886581 Neighboring gene si:ch211-37e10.1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Focal adhesions are essential to drive zebrafish heart valve morphogenesis. Gunawan F, et al. J Cell Biol, 2019 Mar 4. PMID 30635353, Free PMC Article
    2. A new mib allele with a chromosomal deletion covering foxc1a exhibits anterior somite specification defect. Hsu CH, et al. Sci Rep, 2015 Jun 3. PMID 26039894, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC63968

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    amyloid beta A4 precursor protein-binding family B member 1-interacting protein
    Names
    APBB1-interacting protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200634.1 → NP_956928.1  amyloid beta A4 precursor protein-binding family B member 1-interacting protein

      See identical proteins and their annotated locations for NP_956928.1

      Status: VALIDATED

      Source sequence(s)
      BC057421
      UniProtKB/Swiss-Prot
      Q6PFT9
      Related
      ENSDARP00000117778.1, ENSDART00000146830.3
      Conserved Domains (3) summary
      cd01259
      Location:289 → 410
      PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
      pfam00169
      Location:296 → 401
      PH; PH domain
      cl00155
      Location:172 → 246
      UBQ; Ubiquitin-like proteins

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      6040033..6078200 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6PFT9.1 GenPept UniProtKB/Swiss-Prot:Q6PFT9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.