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    PTGES2 prostaglandin E synthase 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 609101, updated on 5-Mar-2024

    Summary

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    Official Symbol
    PTGES2provided by VGNC
    Official Full Name
    prostaglandin E synthase 2provided by VGNC
    Primary source
    VGNC:VGNC:45146
    See related
    Ensembl:ENSCAFG00845029789
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 9
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (56265556..56271558)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (54538207..54543755)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (55431910..55437458)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (55025498..55031060)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (55340213..55345769)

    Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene CDKN1A interacting zinc finger protein 1 Neighboring gene bublin coiled coil protein Neighboring gene 60S ribosomal protein L30-like Neighboring gene lipocalin 2 Neighboring gene solute carrier family 25 member 25 Neighboring gene uncharacterized LOC119873364 Neighboring gene nuclear apoptosis inducing factor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables prostaglandin-E synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    prostaglandin E synthase 2
    NP_001124522.1
    XP_038531024.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001131050.1 → NP_001124522.1  prostaglandin E synthase 2

      See identical proteins and their annotated locations for NP_001124522.1

      Status: PROVISIONAL

      Source sequence(s)
      EU707923
      UniProtKB/TrEMBL
      A0A8C0SNP1, A0A8P0NL47, B4YY03, F1P9X4
      Related
      ENSCAFP00845041418.1, ENSCAFT00845052759.1
      Conserved Domains (2) summary
      cd03197
      Location:221 → 369
      GST_C_mPGES2; C-terminal, alpha helical domain of microsomal Prostaglandin E synthase Type 2
      cd03040
      Location:98 → 174
      GST_N_mPGES2; GST_N family; microsomal Prostaglandin E synthase Type 2 (mPGES2) subfamily; mPGES2 is a membrane-anchored dimeric protein containing a CXXC motif which catalyzes the isomerization of PGH2 to PGE2. Unlike cytosolic PGE synthase (cPGES) and microsomal ...

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051813.1 Reference ROS_Cfam_1.0

      Range
      56265556..56271558
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038675096.1 → XP_038531024.1  prostaglandin E synthase 2 isoform X1

      Conserved Domains (1) summary
      cd03197
      Location:33 → 181
      GST_C_mPGES2; C-terminal, alpha helical domain of microsomal Prostaglandin E synthase Type 2

    RNA

    1. XR_005431692.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049269.1 Alternate UMICH_Zoey_3.1

      Range
      55025498..55031060
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

      Range
      55340213..55345769
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

      Range
      55431910..55437458
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      54538207..54543755
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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