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stat1 signal transducer and activator of transcription 1 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 780397, updated on 5-Mar-2024

Summary

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Official Symbol
stat1provided by Xenbase
Official Full Name
signal transducer and activator of transcription 1provided by Xenbase
Primary source
Xenbase:XB-GENE-482166
See related
Ensembl:ENSXETG00000004649
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
XStat1; isgf-3; stat91
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
25
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 9 NC_030685.2 (43313221..43534806, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 9 NC_030685.1 (43671484..43888385)

Chromosome 9 - NC_030685.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101732225 Neighboring gene uncharacterized LOC101731991 Neighboring gene DnaJ heat shock protein family (Hsp40) member B11 Neighboring gene signal transducer and activator of transcription 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC147452

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
signal transducer and activator of transcription 1-alpha/beta
Names
signal transducer and activator of transcription 1, 91kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079467.1 → NP_001072935.1  signal transducer and activator of transcription 1-alpha/beta

    See identical proteins and their annotated locations for NP_001072935.1

    Status: PROVISIONAL

    Source sequence(s)
    BC124009
    UniProtKB/TrEMBL
    A0A6I8SRU4, Q08D02
    Conserved Domains (4) summary
    smart00964
    Location:2 → 119
    STAT_int; STAT protein, protein interaction domain
    pfam01017
    Location:139 → 315
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:317 → 567
    STAT_bind; STAT protein, DNA binding domain
    cl15255
    Location:558 → 626
    SH2; Src homology 2 (SH2) domain

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030685.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    43313221..43534806 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012970596.3 → XP_012826050.2  signal transducer and activator of transcription 1-alpha/beta isoform X1

    UniProtKB/TrEMBL
    A0A6I8S5E5, F6Q0M0, F6UJK9
    Related
    ENSXETP00000087932.2, ENSXETT00000098027.2
    Conserved Domains (5) summary
    smart00964
    Location:2 → 119
    STAT_int; STAT protein, protein interaction domain
    cd16851
    Location:138 → 313
    STAT1_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 1 (STAT1)
    cd16845
    Location:317 → 477
    STAT1_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 1 (STAT1)
    pfam12162
    Location:714 → 738
    STAT1_TAZ2bind; STAT1 TAZ2 binding domain
    cl15255
    Location:558 → 706
    SH2; Src homology 2 (SH2) domain

  2. XM_018097153.2 → XP_017952642.2  signal transducer and activator of transcription 1-alpha/beta isoform X2

    UniProtKB/TrEMBL
    A0A6I8SRU4, A0A8J0T3P7
    Conserved Domains (4) summary
    cd16851
    Location:138 → 313
    STAT1_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 1 (STAT1)
    cd16845
    Location:317 → 477
    STAT1_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 1 (STAT1)
    pfam02865
    Location:2 → 119
    STAT_int; STAT protein, protein interaction domain
    cl15255
    Location:558 → 624
    SH2; Src homology 2 (SH2) domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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