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LOC6537874 DNA polymerase epsilon catalytic subunit 1 [ Drosophila yakuba ]

Gene ID: 6537874, updated on 14-May-2024

Summary

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Gene symbol
LOC6537874
Gene description
DNA polymerase epsilon catalytic subunit 1
Locus tag
Dyak_GE10366
See related
EnsemblRapid:LOC6537874
Gene type
protein coding
RefSeq status
MODEL
Organism
Drosophila yakuba
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
GE10366; GE10366-PA
Orthologs
fruit fly all
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Genomic context

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Location:
chromosome: 3R
Exon count:
4
Annotation release Status Assembly Chr Location
102 current Prin_Dyak_Tai18E2_2.1 (GCF_016746365.2) 3R NC_052530.2 (21863698..21870746)
101 previous assembly Prin_Dyak_Tai18E2_2.0 (GCF_016746365.1) 3R NC_052530.1 (21863755..21870803)

Chromosome 3R - NC_052530.2Genomic Context describing neighboring genes Neighboring gene glutamate dehydrogenase, mitochondrial Neighboring gene ETS-like protein pointed Neighboring gene ATP synthase-coupling factor 6, mitochondrial Neighboring gene protein SEC13 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolution of genes and genomes on the Drosophila phylogeny. Drosophila 12 Genomes Consortium, et al. Nature, 2007 Nov 8. PMID 17994087

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-directed DNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA 3'-5' DNA exonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA replication proofreading IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in base-excision repair, gap-filling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in leading strand elongation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nucleotide-excision repair, DNA gap filling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of epsilon DNA polymerase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA polymerase epsilon catalytic subunit 1
Names
Dyak\GE10366
Dyak\GE10366-PA
dyak_GLEANR_10297

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Drosophila yakuba Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Prin_Dyak_Tai18E2_2.1 Primary Assembly

Genomic

  1. NC_052530.2 Reference Prin_Dyak_Tai18E2_2.1 Primary Assembly

    Range
    21863698..21870746
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002098379.3 → XP_002098415.1  DNA polymerase epsilon catalytic subunit 1

    See identical proteins and their annotated locations for XP_002098415.1

    UniProtKB/TrEMBL
    B4PN72
    Related
    XP_002098415.1, XM_002098379.3
    Conserved Domains (5) summary
    cd05779
    Location:266 → 469
    DNA_polB_epsilon_exo; DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase epsilon, a family-B DNA polymerase
    cd05535
    Location:529 → 1154
    POLBc_epsilon; DNA polymerase type-B epsilon subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. DNA polymerase (Pol) epsilon has been proposed ...
    smart00486
    Location:265 → 868
    POLBc; DNA polymerase type-B family
    pfam03104
    Location:84 → 425
    DNA_pol_B_exo1; DNA polymerase family B, exonuclease domain
    pfam08490
    Location:1531 → 1930
    DUF1744; Domain of unknown function (DUF1744)
Nucleotide Protein Strain
Heading Accession and Version

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