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FLOT2 flotillin 2 [ Bos taurus (domestic cattle) ]

Gene ID: 615679, updated on 18-Aug-2024

Summary

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Official Symbol
FLOT2provided by VGNC
Official Full Name
flotillin 2provided by VGNC
Primary source
VGNC:VGNC:29037
See related
BGD:BT11857; Ensembl:ENSBTAG00000010073
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (20251609..20269764, complement)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene microRNA mir-451 Neighboring gene microRNA mir-144 Neighboring gene microRNA mir-12059 Neighboring gene dehydrogenase/reductase 13 Neighboring gene PHD finger protein 12 Neighboring gene seizure related 6 homolog

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
  2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in protein localization to plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of myoblast differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
flotillin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001035466.2 → NP_001030543.2  flotillin-2

    See identical proteins and their annotated locations for NP_001030543.2

    Status: VALIDATED

    Source sequence(s)
    BT021803, DV912332, EE369234
    UniProtKB/Swiss-Prot
    A6QLR4
    UniProtKB/TrEMBL
    A0A3Q1MR39
    Conserved Domains (2) summary
    COG2268
    Location:6 → 417
    YqiK; Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]
    cd03399
    Location:34 → 178
    SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    20251609..20269764 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059878240.1 → XP_059734223.1  flotillin-2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1MR39

  2. XM_024980427.2 → XP_024836195.1  flotillin-2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MR39
    Conserved Domains (2) summary
    COG2268
    Location:6 → 417
    YqiK; Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]
    cd03399
    Location:34 → 178
    SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

  3. XM_024980431.2 → XP_024836199.1  flotillin-2 isoform X4

    Related
    ENSBTAP00000074151.2, ENSBTAT00000066446.2
    Conserved Domains (2) summary
    COG2268
    Location:8 → 340
    YqiK; Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]
    cd03399
    Location:1 → 101
    SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

  4. XM_059878241.1 → XP_059734224.1  flotillin-2 isoform X3

    UniProtKB/TrEMBL
    A0A3Q1MR39
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A6QLR4.1 GenPept UniProtKB/Swiss-Prot:A6QLR4

Gene LinkOut

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