PDK4 pyruvate dehydrogenase kinase 4 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: PDK4provided by VGNC
Official Full Name: pyruvate dehydrogenase kinase 4provided by VGNC
Primary source: VGNC:VGNC:32706
See related: BGD:BT11731; Ensembl:ENSBTAG00000014069
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	4	NC_037331.1 (12881889..12895362, complement)

Chromosome 4 - NC_037331.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables pyruvate dehydrogenase (acetyl-transferring) kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of glucose metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: pyruvate dehydrogenase kinase 4

Names: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial; pyruvate dehydrogenase kinase, isozyme 4

NP_001095353.1

EC 2.7.11.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001101883.1 → NP_001095353.1 pyruvate dehydrogenase kinase 4

See identical proteins and their annotated locations for NP_001095353.1

Status: PROVISIONAL

Source sequence(s)

BC150114

UniProtKB/TrEMBL

A6QR49, F1N1X5

Related

ENSBTAP00000038686.5, ENSBTAT00000038879.5

Conserved Domains (3) summary

smart00387
Location:240 → 360

HATPase_c; Histidine kinase-like ATPases

COG0642
Location:49 → 368

BaeS; Signal transduction histidine kinase [Signal transduction mechanisms]

pfam10436
Location:29 → 190

BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase