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IRAK1 interleukin 1 receptor associated kinase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 492247, updated on 5-Mar-2024

Summary

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Official Symbol
IRAK1provided by VGNC
Official Full Name
interleukin 1 receptor associated kinase 1provided by VGNC
Primary source
VGNC:VGNC:42087
See related
Ensembl:ENSCAFG00845027126
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See IRAK1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (124993051..125003852, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (107180516..107191312, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (123039025..123049823, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (120762292..120773086, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (123277991..123288705, complement)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 187 Neighboring gene uncharacterized LOC119868252 Neighboring gene microRNA mir-718 Neighboring gene methyl-CpG binding protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in interleukin-1-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: interleukin-1 receptor-associated kinase 1; interleukin-1 receptor-associated kinase 1
XP_022271598.1
XP_038307195.1
XP_038307196.1
XP_038380664.1
XP_038380665.1
XP_038444627.1
XP_038444628.1
XP_038509148.1
XP_549367.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    124993051..125003852 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038451268.1 → XP_038307196.1  interleukin-1 receptor-associated kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Z301, A0A8C0Z309, A0A8I3PV99
    Related
    ENSCAFP00845037512.1, ENSCAFT00845047807.1
    Conserved Domains (2) summary
    cd08794
    Location:17 → 100
    Death_IRAK1; Death domain of Interleukin 1 Receptor Associated Kinase-1
    cl21453
    Location:219 → 522
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038451267.1 → XP_038307195.1  interleukin-1 receptor-associated kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0Z309, A0A8I3PV99
    Conserved Domains (2) summary
    cd08794
    Location:17 → 100
    Death_IRAK1; Death domain of Interleukin 1 Receptor Associated Kinase-1
    cl21453
    Location:219 → 542
    PKc_like; Protein Kinases, catalytic domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    120762292..120773086 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038524737.1 → XP_038380665.1  interleukin-1 receptor-associated kinase 1 isoform X2

    Conserved Domains (2) summary
    cd08794
    Location:17 → 100
    Death_IRAK1; Death domain of Interleukin 1 Receptor Associated Kinase-1
    cl21453
    Location:219 → 522
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038524736.1 → XP_038380664.1  interleukin-1 receptor-associated kinase 1 isoform X1

    Conserved Domains (2) summary
    cd08794
    Location:17 → 100
    Death_IRAK1; Death domain of Interleukin 1 Receptor Associated Kinase-1
    cl21453
    Location:219 → 542
    PKc_like; Protein Kinases, catalytic domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    123277991..123288705 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038653220.1 → XP_038509148.1  LOW QUALITY PROTEIN: interleukin-1 receptor-associated kinase 1 isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    123039025..123049823 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038588700.1 → XP_038444628.1  interleukin-1 receptor-associated kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Z301, A0A8C0Z309, A0A8I3PV99
    Conserved Domains (2) summary
    cd08794
    Location:17 → 100
    Death_IRAK1; Death domain of Interleukin 1 Receptor Associated Kinase-1
    cl21453
    Location:219 → 522
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038588699.1 → XP_038444627.1  interleukin-1 receptor-associated kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0Z309, A0A8I3PV99
    Conserved Domains (2) summary
    cd08794
    Location:17 → 100
    Death_IRAK1; Death domain of Interleukin 1 Receptor Associated Kinase-1
    cl21453
    Location:219 → 542
    PKc_like; Protein Kinases, catalytic domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    107180516..107191312 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_549367.7 → XP_549367.2  interleukin-1 receptor-associated kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Z301, A0A8C0Z309, A0A8I3PV99
    Conserved Domains (2) summary
    cd08794
    Location:17 → 100
    Death_IRAK1; Death domain of Interleukin 1 Receptor Associated Kinase-1
    cl21453
    Location:219 → 522
    PKc_like; Protein Kinases, catalytic domain

  2. XM_022415890.2 → XP_022271598.1  interleukin-1 receptor-associated kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0Z309, A0A8I3PV99
    Conserved Domains (2) summary
    cd08794
    Location:17 → 100
    Death_IRAK1; Death domain of Interleukin 1 Receptor Associated Kinase-1
    cl21453
    Location:219 → 542
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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