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GLRX3 glutaredoxin 3 [ Canis lupus familiaris (dog) ]

Gene ID: 477869, updated on 5-Mar-2024

Summary

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Official Symbol
GLRX3provided by VGNC
Official Full Name
glutaredoxin 3provided by VGNC
Primary source
VGNC:VGNC:41275
See related
Ensembl:ENSCAFG00845028498
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
TXNL2
Orthologs
human mouse all
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Genomic context

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See GLRX3 in Genome Data Viewer
Location:
chromosome: 28
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 28 NC_051832.1 (39360801..39391612)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 28 NC_006610.4 (38781705..38812290)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 28 NC_049249.1 (39090506..39121238)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 28 NC_049288.1 (38847851..38878212)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 28 NC_049769.1 (38836160..38866776)

Chromosome 28 - NC_051832.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106557926 Neighboring gene EBF transcription factor 3 Neighboring gene chromosome 28 C10orf143 homolog Neighboring gene uncharacterized LOC119866622 Neighboring gene uncharacterized LOC102152832 Neighboring gene uncharacterized LOC111093053

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
glutaredoxin-3
Names
thioredoxin-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051832.1 Reference ROS_Cfam_1.0

    Range
    39360801..39391612
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038440954.1 → XP_038296882.1  glutaredoxin-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L681, A0A8C0TKL9, A0A8I3Q4L8, A0A8I3SBI2, A0A8P0TAI6
    Related
    ENSCAFP00845039460.1, ENSCAFT00845050332.1
    Conserved Domains (2) summary
    cd02984
    Location:16 → 111
    TRX_PICOT; TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an ...
    cd03028
    Location:135 → 223
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...

  2. XM_038440956.1 → XP_038296884.1  glutaredoxin-3 isoform X3

    UniProtKB/TrEMBL
    A0A8I3SBI2, A0A8P0TAI6
    Conserved Domains (3) summary
    cd02984
    Location:16 → 111
    TRX_PICOT; TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an ...
    cd03028
    Location:135 → 223
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
    cl00388
    Location:237 → 286
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

  3. XM_038440958.1 → XP_038296886.1  glutaredoxin-3 isoform X4

    UniProtKB/TrEMBL
    A0A8I3SBI2, A0A8P0TAI6
    Conserved Domains (2) summary
    cd03028
    Location:89 → 177
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
    PTZ00062
    Location:3 → 182
    PTZ00062; glutaredoxin; Provisional

  4. XM_038440955.1 → XP_038296883.1  glutaredoxin-3 isoform X2

    UniProtKB/TrEMBL
    A0A8I3SBI2, A0A8P0TAI6
    Conserved Domains (2) summary
    cd02984
    Location:9 → 95
    TRX_PICOT; TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an ...
    cd03028
    Location:119 → 207
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...

  5. XM_038440957.1 → XP_038296885.1  glutaredoxin-3 isoform X4

    UniProtKB/TrEMBL
    A0A8I3SBI2, A0A8P0TAI6
    Conserved Domains (2) summary
    cd03028
    Location:89 → 177
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
    PTZ00062
    Location:3 → 182
    PTZ00062; glutaredoxin; Provisional

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049288.1 Alternate UMICH_Zoey_3.1

    Range
    38847851..38878212
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038515546.1 → XP_038371474.1  glutaredoxin-3 isoform X1

    Conserved Domains (2) summary
    cd02984
    Location:16 → 111
    TRX_PICOT; TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an ...
    cd03028
    Location:135 → 223
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...

  2. XM_038515548.1 → XP_038371476.1  glutaredoxin-3 isoform X3

    Conserved Domains (3) summary
    cd02984
    Location:16 → 111
    TRX_PICOT; TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an ...
    cd03028
    Location:135 → 223
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
    cl00388
    Location:237 → 286
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

  3. XM_038515550.1 → XP_038371478.1  glutaredoxin-3 isoform X4

    Conserved Domains (2) summary
    cd03028
    Location:89 → 177
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
    PTZ00062
    Location:3 → 182
    PTZ00062; glutaredoxin; Provisional

  4. XM_038515547.1 → XP_038371475.1  glutaredoxin-3 isoform X2

    Conserved Domains (2) summary
    cd02984
    Location:9 → 95
    TRX_PICOT; TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an ...
    cd03028
    Location:119 → 207
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...

  5. XM_038515549.1 → XP_038371477.1  glutaredoxin-3 isoform X4

    Conserved Domains (2) summary
    cd03028
    Location:89 → 177
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
    PTZ00062
    Location:3 → 182
    PTZ00062; glutaredoxin; Provisional

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049769.1 Alternate UNSW_CanFamBas_1.0

    Range
    38836160..38866776
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038643372.1 → XP_038499300.1  glutaredoxin-3 isoform X1

    Conserved Domains (2) summary
    cd02984
    Location:16 → 111
    TRX_PICOT; TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an ...
    cd03028
    Location:135 → 223
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...

  2. XM_038643374.1 → XP_038499302.1  glutaredoxin-3 isoform X3

    Conserved Domains (3) summary
    cd02984
    Location:16 → 111
    TRX_PICOT; TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an ...
    cd03028
    Location:135 → 223
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
    cl00388
    Location:237 → 286
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

  3. XM_038643376.1 → XP_038499304.1  glutaredoxin-3 isoform X4

    Conserved Domains (2) summary
    cd03028
    Location:89 → 177
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
    PTZ00062
    Location:3 → 182
    PTZ00062; glutaredoxin; Provisional

  4. XM_038643373.1 → XP_038499301.1  glutaredoxin-3 isoform X2

    Conserved Domains (2) summary
    cd02984
    Location:9 → 95
    TRX_PICOT; TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an ...
    cd03028
    Location:119 → 207
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...

  5. XM_038643375.1 → XP_038499303.1  glutaredoxin-3 isoform X4

    Conserved Domains (2) summary
    cd03028
    Location:89 → 177
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
    PTZ00062
    Location:3 → 182
    PTZ00062; glutaredoxin; Provisional

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049249.1 Alternate UU_Cfam_GSD_1.0

    Range
    39090506..39121238
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038579140.1 → XP_038435068.1  glutaredoxin-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L681, A0A8C0TKL9, A0A8I3Q4L8, A0A8I3SBI2, A0A8P0TAI6
    Conserved Domains (2) summary
    cd02984
    Location:16 → 111
    TRX_PICOT; TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an ...
    cd03028
    Location:135 → 223
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...

  2. XM_038579142.1 → XP_038435070.1  glutaredoxin-3 isoform X3

    UniProtKB/TrEMBL
    A0A8I3SBI2, A0A8P0TAI6
    Conserved Domains (3) summary
    cd02984
    Location:16 → 111
    TRX_PICOT; TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an ...
    cd03028
    Location:135 → 223
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
    cl00388
    Location:237 → 286
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

  3. XM_038579145.1 → XP_038435073.1  glutaredoxin-3 isoform X4

    UniProtKB/TrEMBL
    A0A8I3SBI2, A0A8P0TAI6
    Conserved Domains (2) summary
    cd03028
    Location:89 → 177
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
    PTZ00062
    Location:3 → 182
    PTZ00062; glutaredoxin; Provisional

  4. XM_038579141.1 → XP_038435069.1  glutaredoxin-3 isoform X2

    UniProtKB/TrEMBL
    A0A8I3SBI2, A0A8P0TAI6
    Conserved Domains (2) summary
    cd02984
    Location:9 → 95
    TRX_PICOT; TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an ...
    cd03028
    Location:119 → 207
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...

  5. XM_038579144.1 → XP_038435072.1  glutaredoxin-3 isoform X4

    UniProtKB/TrEMBL
    A0A8I3SBI2, A0A8P0TAI6
    Conserved Domains (2) summary
    cd03028
    Location:89 → 177
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
    PTZ00062
    Location:3 → 182
    PTZ00062; glutaredoxin; Provisional

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006610.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    38781705..38812290
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_535061.7 → XP_535061.2  glutaredoxin-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L681, A0A8C0TKL9, A0A8I3Q4L8, A0A8I3SBI2, A0A8P0TAI6
    Conserved Domains (2) summary
    cd02984
    Location:16 → 111
    TRX_PICOT; TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an ...
    cd03028
    Location:135 → 223
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...

  2. XM_022411730.2 → XP_022267438.1  glutaredoxin-3 isoform X3

    UniProtKB/TrEMBL
    A0A8I3SBI2, A0A8P0TAI6
    Conserved Domains (3) summary
    cd02984
    Location:16 → 111
    TRX_PICOT; TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an ...
    cd03028
    Location:135 → 223
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
    cl00388
    Location:237 → 286
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

  3. XM_022411732.2 → XP_022267440.1  glutaredoxin-3 isoform X4

    UniProtKB/TrEMBL
    A0A8I3SBI2, A0A8P0TAI6
    Conserved Domains (2) summary
    cd03028
    Location:89 → 177
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
    PTZ00062
    Location:3 → 182
    PTZ00062; glutaredoxin; Provisional

  4. XM_022411729.2 → XP_022267437.1  glutaredoxin-3 isoform X2

    UniProtKB/TrEMBL
    A0A8I3SBI2, A0A8P0TAI6
    Conserved Domains (2) summary
    cd02984
    Location:9 → 95
    TRX_PICOT; TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an ...
    cd03028
    Location:119 → 207
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...

  5. XM_022411731.2 → XP_022267439.1  glutaredoxin-3 isoform X4

    UniProtKB/TrEMBL
    A0A8I3SBI2, A0A8P0TAI6
    Conserved Domains (2) summary
    cd03028
    Location:89 → 177
    GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
    PTZ00062
    Location:3 → 182
    PTZ00062; glutaredoxin; Provisional
Nucleotide Protein
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