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LCP1 lymphocyte cytosolic protein 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 452583, updated on 17-Aug-2024

Summary

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Official Symbol
LCP1provided by VGNC
Official Full Name
lymphocyte cytosolic protein 1provided by VGNC
Primary source
VGNC:VGNC:9792
Locus tag
CK820_G0019545
See related
Ensembl:ENSPTRG00000005853
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 14 NC_072412.2 (44715209..44801214)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 13 NC_072411.1 (39497822..39583827)

Chromosome 14 - NC_072412.2Genomic Context describing neighboring genes Neighboring gene protein Abitram-like Neighboring gene leucine rich repeat containing 63 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC107968095 Neighboring gene carboxypeptidase B2 Neighboring gene zinc finger CCCH-type containing 13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin filament bundle assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in actin filament network formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in actin filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in actin filament bundle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
plastin-2
Names
L-plastin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072412.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    44715209..44801214
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054665285.2 → XP_054521260.1  plastin-2

    UniProtKB/TrEMBL
    A0A2I3RWX8, A0A2J8ML27, A0A6D2WV74, H2Q7J2

  2. XM_054665282.2 → XP_054521257.1  plastin-2

    UniProtKB/TrEMBL
    A0A2I3RWX8, A0A2J8ML27, A0A6D2WV74, H2Q7J2

  3. XM_009440614.4 → XP_009438889.1  plastin-2

    See identical proteins and their annotated locations for XP_009438889.1

    UniProtKB/TrEMBL
    A0A2I3RWX8, A0A2J8ML27, A0A6D2WV74, H2Q7J2
    Conserved Domains (5) summary
    cd00051
    Location:13 → 79
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd21292
    Location:98 → 242
    CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
    cd21327
    Location:251 → 375
    CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
    cd21333
    Location:511 → 625
    CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
    cl00030
    Location:374 → 507
    CH_SF; calponin homology (CH) domain superfamily

  4. XM_054665287.2 → XP_054521262.1  plastin-2

    UniProtKB/TrEMBL
    A0A2I3RWX8, A0A2J8ML27, A0A6D2WV74, H2Q7J2

  5. XM_054665289.2 → XP_054521264.1  plastin-2

    UniProtKB/TrEMBL
    A0A2I3RWX8, A0A2J8ML27, A0A6D2WV74, H2Q7J2

  6. XM_054665283.2 → XP_054521258.1  plastin-2

    UniProtKB/TrEMBL
    A0A2I3RWX8, A0A2J8ML27, A0A6D2WV74, H2Q7J2

  7. XM_054665284.2 → XP_054521259.1  plastin-2

    UniProtKB/TrEMBL
    A0A2I3RWX8, A0A2J8ML27, A0A6D2WV74, H2Q7J2

  8. XM_054665290.2 → XP_054521265.1  plastin-2

    UniProtKB/TrEMBL
    A0A2I3RWX8, A0A2J8ML27, A0A6D2WV74, H2Q7J2

  9. XM_063792503.1 → XP_063648573.1  plastin-2

    UniProtKB/TrEMBL
    A0A2I3RWX8, A0A2J8ML27, A0A6D2WV74, H2Q7J2

  10. XM_054665288.2 → XP_054521263.1  plastin-2

    UniProtKB/TrEMBL
    A0A2I3RWX8, A0A2J8ML27, A0A6D2WV74, H2Q7J2

  11. XM_001157685.7 → XP_001157685.3  plastin-2

    See identical proteins and their annotated locations for XP_001157685.3

    UniProtKB/TrEMBL
    A0A2I3RWX8, A0A2J8ML27, A0A6D2WV74, H2Q7J2
    Related
    ENSPTRP00000009959.2
    Conserved Domains (5) summary
    cd00051
    Location:13 → 79
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd21292
    Location:98 → 242
    CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
    cd21327
    Location:251 → 375
    CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
    cd21333
    Location:511 → 625
    CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
    cl00030
    Location:374 → 507
    CH_SF; calponin homology (CH) domain superfamily
Nucleotide Protein
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