SMC5 structural maintenance of chromosomes 5 [Gallus gallus (chicken)] - Gene

Summary

Symbol: SMC5provided by CGNC
Full Name: structural maintenance of chromosomes 5provided by CGNC
Primary source: CGNC:54296
See related: Ensembl:ENSGALG00010014971
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: SMC-5; SMC5L1
Orthologs: human mouse all
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Genomic context

Location:: chromosome: Z

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	Z	NC_052572.1 (35566563..35621565)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	Z	NC_059536.1 (35566563..35621565)

Chromosome Z - NC_052572.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Smc5/6 regulates recombinational repair by ensuring appropriate sister chromatid cohesion.
Title: Roles of vertebrate Smc5 in sister chromatid cohesion and homologous recombinational repair.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in double-strand break repair via homologous recombination	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of Smc5-Smc6 complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: structural maintenance of chromosomes protein 5

Names: RCJMB04_6o14; SMC protein 5; SMC5 structural maintenance of chromosomes 5-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001039335.3 → NP_001034424.2 structural maintenance of chromosomes protein 5

Status: VALIDATED

Source sequence(s)

JAENSK010000094

UniProtKB/Swiss-Prot

Q5F3U6, Q5ZJY5

Related

ENSGALP00010020913.1, ENSGALT00010036022.1

Conserved Domains (3) summary

cd03277
Location:939 → 1041

ABC_SMC5_euk; ATP-binding cassette domain of eukaryotic SMC5 proteins

COG1196
Location:32 → 1019

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

pfam09455
Location:820 → 938

Cas_DxTHG; CRISPR-associated (Cas) DxTHG family