U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MTA1 metastasis associated 1 [ Gallus gallus (chicken) ]

Gene ID: 429060, updated on 3-Apr-2024

Summary

Go to the top of the page Help
Symbol
MTA1provided by CGNC
Full Name
metastasis associated 1provided by CGNC
Primary source
CGNC:53548
See related
Ensembl:ENSGALG00010013251
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See MTA1 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
22
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (4015025..4081342, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (4026713..4093035, complement)

Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene cysteine rich protein 1 Neighboring gene cysteine rich protein 2 Neighboring gene uncharacterized LOC107053927 Neighboring gene uncharacterized LOC112532917 Neighboring gene phosphofurin acidic cluster sorting protein 2 Neighboring gene uncharacterized LOC121113418 Neighboring gene SEC22 homolog B, vesicle trafficking protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to ionizing radiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NuRD complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
metastasis-associated protein MTA1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012953.2 → NP_001012971.2  metastasis-associated protein MTA1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000237
    UniProtKB/TrEMBL
    E1C4P2, Q5ZKS4
    Related
    ENSGALP00010018675.1, ENSGALT00010031872.1
    Conserved Domains (5) summary
    cd11661
    Location:270 → 315
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:372 → 424
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 171
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:150 → 202
    ELM2; ELM2 domain
    pfam17226
    Location:447 → 524
    MTA_R1; MTA R1 domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    4015025..4081342 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015290320.4 → XP_015145806.1  metastasis-associated protein MTA1 isoform X3

    UniProtKB/TrEMBL
    A0A8V0YLB2
    Related
    ENSGALP00010018670.1, ENSGALT00010031866.1
    Conserved Domains (5) summary
    cd11661
    Location:270 → 315
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:372 → 424
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 171
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:150 → 202
    ELM2; ELM2 domain
    pfam17226
    Location:447 → 524
    MTA_R1; MTA R1 domain

  2. XM_015290319.4 → XP_015145805.1  metastasis-associated protein MTA1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0YLB2
    Related
    ENSGALP00010018661.1, ENSGALT00010031857.1
    Conserved Domains (5) summary
    cd11661
    Location:270 → 315
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:372 → 424
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 171
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:150 → 202
    ELM2; ELM2 domain
    pfam17226
    Location:447 → 524
    MTA_R1; MTA R1 domain

  3. XM_015290318.4 → XP_015145804.1  metastasis-associated protein MTA1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YLB2
    Conserved Domains (5) summary
    cd11661
    Location:270 → 315
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:372 → 424
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 171
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:150 → 202
    ELM2; ELM2 domain
    pfam17226
    Location:447 → 524
    MTA_R1; MTA R1 domain

  4. XM_040704721.2 → XP_040560655.1  metastasis-associated protein MTA1 isoform X5

    UniProtKB/TrEMBL
    A0A8V0YLB2
    Conserved Domains (3) summary
    cd11661
    Location:205 → 250
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:307 → 359
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cl02608
    Location:12 → 106
    BAH; or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in ...

  5. XM_040704720.2 → XP_040560654.1  metastasis-associated protein MTA1 isoform X4

    UniProtKB/TrEMBL
    E1C4P2, Q5ZKS4
    Related
    ENSGALP00010018668.1, ENSGALT00010031864.1
    Conserved Domains (5) summary
    cd11661
    Location:270 → 315
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:372 → 424
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 171
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:150 → 202
    ELM2; ELM2 domain
    pfam17226
    Location:447 → 524
    MTA_R1; MTA R1 domain

  6. XM_015290322.4 → XP_015145808.1  metastasis-associated protein MTA1 isoform X6

    Conserved Domains (3) summary
    cd11661
    Location:270 → 315
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    cd04709
    Location:3 → 171
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:150 → 202
    ELM2; ELM2 domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    4026713..4093035 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046922951.1 → XP_046778907.1  metastasis-associated protein MTA1 isoform X3

  2. XM_046922950.1 → XP_046778906.1  metastasis-associated protein MTA1 isoform X2

  3. XM_046922949.1 → XP_046778905.1  metastasis-associated protein MTA1 isoform X1

  4. XM_046922955.1 → XP_046778911.1  metastasis-associated protein MTA1 isoform X5

  5. XM_046922952.1 → XP_046778908.1  metastasis-associated protein MTA1 isoform X7

  6. XM_046922953.1 → XP_046778909.1  metastasis-associated protein MTA1 isoform X7

  7. XM_046922954.1 → XP_046778910.1  metastasis-associated protein MTA1 isoform X4

    UniProtKB/TrEMBL
    E1C4P2
    Conserved Domains (5) summary
    cd11661
    Location:270 → 315
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:372 → 424
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 171
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:150 → 202
    ELM2; ELM2 domain
    pfam17226
    Location:447 → 524
    MTA_R1; MTA R1 domain

  8. XM_046922956.1 → XP_046778912.1  metastasis-associated protein MTA1 isoform X6

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous