TARS threonyl-tRNA synthetase [Gallus gallus (chicken)] - Gene

Summary

Symbol: TARSprovided by CGNC
Full Name: threonyl-tRNA synthetaseprovided by CGNC
Primary source: CGNC:53084
See related: Ensembl:ENSGALG00010013116
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: Z

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	Z	NC_052572.1 (10656285..10670899)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	Z	NC_059536.1 (10656285..10670899)

Chromosome Z - NC_052572.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables threonine-tRNA ligase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in threonyl-tRNA aminoacylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: threonine--tRNA ligase 1, cytoplasmic

Names: threonyl-tRNA synthetase, cytoplasmic

NP_001026618.1

EC 6.1.1.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001031447.1 → NP_001026618.1 threonine--tRNA ligase 1, cytoplasmic

See identical proteins and their annotated locations for NP_001026618.1

Status: PROVISIONAL

Source sequence(s)

AJ719623

UniProtKB/TrEMBL

A0A8V0YQC4, E1C8M1, Q5ZLW1

Related

ENSGALP00010018358.1, ENSGALT00010031446.1

Conserved Domains (5) summary

cd01667
Location:71 → 132

TGS_ThrRS_N; TGS _ThrRS_N: ThrRS (threonyl-tRNA Synthetase) is a class II tRNA synthetase that couples threonine to its cognate tRNA. In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and ...

PLN02908
Location:25 → 704

PLN02908; threonyl-tRNA synthetase

smart00863
Location:238 → 285

tRNA_SAD; Threonyl and Alanyl tRNA synthetase second additional domain

cd00771
Location:309 → 606

ThrRS_core; Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent ...

cd00860
Location:606 → 697

ThrRS_anticodon; ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is ...