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ACLY ATP citrate lyase [ Gallus gallus (chicken) ]

Gene ID: 395373, updated on 17-Aug-2024

Summary

Symbol
ACLYprovided by CGNC
Full Name
ATP citrate lyaseprovided by CGNC
Primary source
CGNC:2533
See related
Ensembl:ENSGALG00010022919
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
ACL
Orthologs
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Genomic context

Location:
chromosome: 27
Exon count:
40
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 27 NC_052558.1 (4699738..4730001, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 27 NC_052599.1 (5861938..5892228, complement)

Chromosome 27 - NC_052558.1Genomic Context describing neighboring genes Neighboring gene kelch like family member 10 Neighboring gene kelch like family member 11 Neighboring gene tetratricopeptide repeat domain 25 Neighboring gene 2',3'-cyclic nucleotide 3' phosphodiesterase Neighboring gene DnaJ heat shock protein family (Hsp40) member C7 Neighboring gene NFKB inhibitor interacting Ras like 2

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP citrate synthase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in citrate metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
ATP-citrate synthase
NP_001025711.2
XP_015155056.1
XP_015155058.1
XP_015155059.1
XP_015155060.1
XP_015155061.1
XP_015155062.1
XP_015155063.1
XP_015155064.1
XP_015155065.1
XP_015155066.1
XP_024999710.1
XP_040509002.1
XP_040509003.1
XP_040509004.1
XP_040509005.1
XP_040509006.1
XP_040509007.1
XP_046760273.1
XP_046760274.1
XP_046760275.1
XP_046760276.1
XP_046789166.1
XP_046789167.1
XP_046789168.1
XP_046789169.1
XP_046789170.1
XP_046789171.1
XP_046789172.1
XP_046789173.1
XP_046789174.1
XP_046789175.1
XP_046789176.1
XP_046789177.1
XP_046789178.1
XP_046789179.1
XP_046789180.1
XP_046789181.1
XP_046789182.1
XP_046789183.1
XP_046789184.1
XP_046789185.1
XP_046789186.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030540.2NP_001025711.2  ATP-citrate synthase

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000365
    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
    Related
    ENSGALP00010033780.1, ENSGALT00010055798.1
    Conserved Domains (2) summary
    PLN02522
    Location:4911094
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1419
    Citrate_bind; ATP citrate lyase citrate-binding

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052558.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    4699738..4730001 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046904319.1XP_046760275.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
  2. XM_046904317.1XP_046760273.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
  3. XM_046904318.1XP_046760274.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
  4. XM_015299570.4XP_015155056.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
    Conserved Domains (2) summary
    PLN02522
    Location:4911094
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1419
    Citrate_bind; ATP citrate lyase citrate-binding
  5. XM_040653071.2XP_040509005.1  ATP-citrate synthase isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZQM1
    Conserved Domains (2) summary
    PLN02522
    Location:4811084
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1419
    Citrate_bind; ATP citrate lyase citrate-binding
  6. XM_015299575.4XP_015155061.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
    Conserved Domains (2) summary
    PLN02522
    Location:4911094
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1419
    Citrate_bind; ATP citrate lyase citrate-binding
  7. XM_040653072.2XP_040509006.1  ATP-citrate synthase isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZQM1
    Conserved Domains (2) summary
    PLN02522
    Location:4811084
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1419
    Citrate_bind; ATP citrate lyase citrate-binding
  8. XM_015299576.4XP_015155062.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
    Conserved Domains (2) summary
    PLN02522
    Location:4911094
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1419
    Citrate_bind; ATP citrate lyase citrate-binding
  9. XM_015299578.4XP_015155064.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
    Conserved Domains (2) summary
    PLN02522
    Location:4911094
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1419
    Citrate_bind; ATP citrate lyase citrate-binding
  10. XM_040653069.2XP_040509003.1  ATP-citrate synthase isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZQM1
    Conserved Domains (2) summary
    PLN02522
    Location:4811084
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1419
    Citrate_bind; ATP citrate lyase citrate-binding
  11. XM_015299573.4XP_015155059.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
    Conserved Domains (2) summary
    PLN02522
    Location:4911094
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1419
    Citrate_bind; ATP citrate lyase citrate-binding
  12. XM_040653070.2XP_040509004.1  ATP-citrate synthase isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZQM1
    Related
    ENSGALP00010033790.1, ENSGALT00010055812.1
    Conserved Domains (2) summary
    PLN02522
    Location:4811084
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1419
    Citrate_bind; ATP citrate lyase citrate-binding
  13. XM_015299572.4XP_015155058.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
    Conserved Domains (2) summary
    PLN02522
    Location:4911094
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1419
    Citrate_bind; ATP citrate lyase citrate-binding
  14. XM_040653073.2XP_040509007.1  ATP-citrate synthase isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZQM1
    Conserved Domains (2) summary
    PLN02522
    Location:4801083
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1418
    Citrate_bind; ATP citrate lyase citrate-binding
  15. XM_015299580.4XP_015155066.1  ATP-citrate synthase isoform X2

    UniProtKB/TrEMBL
    Q5F3V2
    Conserved Domains (7) summary
    cd06100
    Location:8551092
    CCL_ACL-C; Citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CCL cleaves citryl-CoA (CiCoA) to acetyl-CoA (AcCoA) and oxaloacetate (OAA). ...
    PLN02235
    Location:1418
    PLN02235; ATP citrate (pro-S)-lyase
    PLN02522
    Location:4901093
    PLN02522; ATP citrate (pro-S)-lyase
    pfam16114
    Location:246420
    Citrate_bind; ATP citrate lyase citrate-binding
    cl17255
    Location:55206
    ATP-grasp_4; ATP-grasp domain
    cl21454
    Location:496599
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    cl22543
    Location:659784
    Ligase_CoA; CoA-ligase
  16. XM_040653068.2XP_040509002.1  ATP-citrate synthase isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZQM1
    Related
    ENSGALP00010033775.1, ENSGALT00010055787.1
    Conserved Domains (2) summary
    PLN02522
    Location:4811084
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1419
    Citrate_bind; ATP citrate lyase citrate-binding
  17. XM_015299577.4XP_015155063.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
    Conserved Domains (2) summary
    PLN02522
    Location:4911094
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1419
    Citrate_bind; ATP citrate lyase citrate-binding
  18. XM_046904320.1XP_046760276.1  ATP-citrate synthase isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZQM1
  19. XM_015299574.4XP_015155060.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
    Conserved Domains (2) summary
    PLN02522
    Location:4911094
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1419
    Citrate_bind; ATP citrate lyase citrate-binding
  20. XM_025143942.3XP_024999710.1  ATP-citrate synthase isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZQM1
    Conserved Domains (2) summary
    PLN02522
    Location:4811084
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1419
    Citrate_bind; ATP citrate lyase citrate-binding
  21. XM_015299579.4XP_015155065.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
    Conserved Domains (2) summary
    PLN02522
    Location:4911094
    PLN02522; ATP citrate (pro-S)-lyase
    cl29684
    Location:1419
    Citrate_bind; ATP citrate lyase citrate-binding

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052599.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    5861938..5892228 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046933214.1XP_046789170.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
  2. XM_046933213.1XP_046789169.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
  3. XM_046933211.1XP_046789167.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
  4. XM_046933212.1XP_046789168.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
  5. XM_046933227.1XP_046789183.1  ATP-citrate synthase isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZQM1
  6. XM_046933216.1XP_046789172.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
  7. XM_046933224.1XP_046789180.1  ATP-citrate synthase isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZQM1
  8. XM_046933217.1XP_046789173.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
  9. XM_046933221.1XP_046789177.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
  10. XM_046933225.1XP_046789181.1  ATP-citrate synthase isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZQM1
  11. XM_046933210.1XP_046789166.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
  12. XM_046933226.1XP_046789182.1  ATP-citrate synthase isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZQM1
  13. XM_046933215.1XP_046789171.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
  14. XM_046933230.1XP_046789186.1  ATP-citrate synthase isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZQM1
  15. XM_046933222.1XP_046789178.1  ATP-citrate synthase isoform X2

    UniProtKB/TrEMBL
    Q5F3V2
  16. XM_046933223.1XP_046789179.1  ATP-citrate synthase isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZQM1
  17. XM_046933218.1XP_046789174.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
  18. XM_046933228.1XP_046789184.1  ATP-citrate synthase isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZQM1
  19. XM_046933219.1XP_046789175.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2
  20. XM_046933229.1XP_046789185.1  ATP-citrate synthase isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZQM1
  21. XM_046933220.1XP_046789176.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1D5PSE5, Q5F3V2