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braf B-Raf proto-oncogene, serine/threonine kinase [ Pangasianodon hypophthalmus (striped catfish) ]

Gene ID: 113532073, updated on 15-Mar-2024

Summary

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Gene symbol
braf
Gene description
B-Raf proto-oncogene, serine/threonine kinase
Locus tag
PHYPO_G00090360
See related
EnsemblRapid:ENSPHYG00025009004
Gene type
protein coding
RefSeq status
MODEL
Organism
Pangasianodon hypophthalmus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes; Pangasiidae; Pangasianodon
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 18
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_02 current fPanHyp1.pri (GCF_027358585.1) 18 NC_069727.1 (18847695..18868169)

Chromosome 18 - NC_069727.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 178Bb Neighboring gene mitochondrial ribosomal protein S33 Neighboring gene BTB (POZ) domain containing 11a Neighboring gene cryptochrome circadian regulator 1a

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_069727.1 Chromosome 18 Reference fPanHyp1.pri

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase B-raf

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027358585.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fPanHyp1.pri

Genomic

  1. NC_069727.1 Reference fPanHyp1.pri

    Range
    18847695..18868169
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034313158.2 → XP_034169049.1  serine/threonine-protein kinase B-raf

    UniProtKB/TrEMBL
    A0A5N5LHP4
    Related
    ENSPHYP00025022767.1, ENSPHYT00025024832.1
    Conserved Domains (3) summary
    cd14062
    Location:484 → 736
    STKc_Raf; Catalytic domain of the Serine/Threonine Kinases, Raf (Rapidly Accelerated Fibrosarcoma) kinases
    cd17134
    Location:174 → 252
    RBD_BRAF; Ras-binding domain (RBD) found in serine/threonine-protein kinase BRAF
    cd20871
    Location:250 → 309
    C1_B-Raf; protein kinase C conserved region 1 (C1 domain) found in B-Raf (Rapidly Accelerated Fibrosarcoma) kinase and similar proteins
Nucleotide Protein
Heading Accession and Version

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