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ADAM10 ADAM metallopeptidase domain 10 [ Theropithecus gelada (gelada) ]

Gene ID: 112627561, updated on 15-Mar-2024

Summary

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Gene symbol
ADAM10
Gene description
ADAM metallopeptidase domain 10
See related
Ensembl:ENSTGEG00000018539
Gene type
protein coding
RefSeq status
MODEL
Organism
Theropithecus gelada
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Theropithecus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7a
Exon count:
16
Annotation release Status Assembly Chr Location
100 current Tgel_1.0 (GCF_003255815.1) 7a NC_037674.1 (33906976..34062770, complement)

Chromosome 7a - NC_037674.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112627667 Neighboring gene lipase C, hepatic type Neighboring gene uncharacterized LOC112627668 Neighboring gene small nucleolar RNA U13 Neighboring gene putative heat shock protein HSP 90-beta 4 Neighboring gene small nucleolar RNA U3 Neighboring gene uncharacterized LOC112627806

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037674.1 Chromosome 7a Reference Tgel_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity involved in amyloid precursor protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
disintegrin and metalloproteinase domain-containing protein 10

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Theropithecus gelada Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Tgel_1.0 Primary Assembly

Genomic

  1. NC_037674.1 Reference Tgel_1.0 Primary Assembly

    Range
    33906976..34062770 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025389931.1 → XP_025245716.1  disintegrin and metalloproteinase domain-containing protein 10 isoform X2

    Conserved Domains (3) summary
    smart00050
    Location:435 → 514
    DISIN; Homologues of snake disintegrins
    cd04270
    Location:220 → 428
    ZnMc_TACE_like; Zinc-dependent metalloprotease; TACE_like subfamily. TACE, the tumor-necrosis factor-alpha converting enzyme, releases soluble TNF-alpha from transmembrane pro-TNF-alpha.
    pfam01562
    Location:43 → 156
    Pep_M12B_propep; Reprolysin family propeptide

  2. XM_025389930.1 → XP_025245715.1  disintegrin and metalloproteinase domain-containing protein 10 isoform X1

    UniProtKB/TrEMBL
    A0A8D2FMK8
    Related
    ENSTGEP00000022905.1, ENSTGET00000027339.1
    Conserved Domains (3) summary
    smart00050
    Location:466 → 545
    DISIN; Homologues of snake disintegrins
    cd04270
    Location:220 → 459
    ZnMc_TACE_like; Zinc-dependent metalloprotease; TACE_like subfamily. TACE, the tumor-necrosis factor-alpha converting enzyme, releases soluble TNF-alpha from transmembrane pro-TNF-alpha.
    pfam01562
    Location:46 → 156
    Pep_M12B_propep; Reprolysin family propeptide
Nucleotide Protein
Heading Accession and Version

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