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SIRT2 sirtuin 2 [ Theropithecus gelada (gelada) ]

Gene ID: 112612948, updated on 15-Mar-2024

Summary

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Gene symbol
SIRT2
Gene description
sirtuin 2
See related
Ensembl:ENSTGEG00000003322
Gene type
protein coding
RefSeq status
MODEL
Organism
Theropithecus gelada
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Theropithecus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
16
Annotation release Status Assembly Chr Location
100 current Tgel_1.0 (GCF_003255815.1) 19 NC_037687.1 (41149367..41176778)

Chromosome 19 - NC_037687.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein S12 Neighboring gene seryl-tRNA synthetase 2, mitochondrial Neighboring gene coiled-coil glutamate rich protein 2 Neighboring gene NFKB inhibitor beta Neighboring gene Ras and Rab interactor like Neighboring gene heterogeneous nuclear ribonucleoprotein L

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037687.1 Chromosome 19 Reference Tgel_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD+ binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables NAD-dependent histone deacetylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NAD-dependent protein deacetylase sirtuin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Theropithecus gelada Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Tgel_1.0 Primary Assembly

Genomic

  1. NC_037687.1 Reference Tgel_1.0 Primary Assembly

    Range
    41149367..41176778
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025367966.1 → XP_025223751.1  NAD-dependent protein deacetylase sirtuin-2 isoform X3

    UniProtKB/TrEMBL
    A0A8D2JV91
    Conserved Domains (1) summary
    cd01408
    Location:40 → 294
    SIRT1; SIRT1: Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 ...

  2. XM_025367971.1 → XP_025223756.1  NAD-dependent protein deacetylase sirtuin-2 isoform X7

    UniProtKB/TrEMBL
    A0A8D2EBM6
    Conserved Domains (1) summary
    cd01408
    Location:40 → 228
    SIRT1; Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins ...

  3. XM_025367965.1 → XP_025223750.1  NAD-dependent protein deacetylase sirtuin-2 isoform X2

    UniProtKB/TrEMBL
    A0A8D2EAM7, A0A8D2JV91
    Related
    ENSTGEP00000003949.1, ENSTGET00000004808.1
    Conserved Domains (1) summary
    cd01408
    Location:77 → 331
    SIRT1; SIRT1: Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 ...

  4. XM_025367969.1 → XP_025223754.1  NAD-dependent protein deacetylase sirtuin-2 isoform X5

    Conserved Domains (1) summary
    cl00195
    Location:77 → 248
    SIR2; SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, ...

  5. XM_025367970.1 → XP_025223755.1  NAD-dependent protein deacetylase sirtuin-2 isoform X6

    UniProtKB/TrEMBL
    A0A8D2JV91
    Conserved Domains (1) summary
    cd01408
    Location:7 → 261
    SIRT1; SIRT1: Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 ...

  6. XM_025367967.1 → XP_025223752.1  NAD-dependent protein deacetylase sirtuin-2 isoform X4

    UniProtKB/TrEMBL
    A0A8D2JV91
    Related
    ENSTGEP00000003953.1, ENSTGET00000004813.1
    Conserved Domains (1) summary
    cd01408
    Location:40 → 294
    SIRT1; SIRT1: Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 ...

  7. XM_025367972.1 → XP_025223757.1  NAD-dependent protein deacetylase sirtuin-2 isoform X8

    UniProtKB/TrEMBL
    A0A8D2EBM6
    Related
    ENSTGEP00000003958.1, ENSTGET00000004818.1
    Conserved Domains (1) summary
    cd01408
    Location:40 → 228
    SIRT1; Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins ...

  8. XM_025367964.1 → XP_025223749.1  NAD-dependent protein deacetylase sirtuin-2 isoform X1

    Conserved Domains (1) summary
    cd01408
    Location:217 → 471
    SIRT1; Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins ...
Nucleotide Protein
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