U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SIRT4 sirtuin 4 [ Neomonachus schauinslandi (Hawaiian monk seal) ]

Gene ID: 110592516, updated on 25-Apr-2024

Summary

Go to the top of the page Help
Gene symbol
SIRT4
Gene description
sirtuin 4
See related
EnsemblRapid:ENSNSCG00000023420
Gene type
protein coding
RefSeq status
MODEL
Organism
Neomonachus schauinslandi
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Neomonachus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 14
Exon count:
3
Annotation release Status Assembly Chr Location
101 current ASM220157v2 (GCF_002201575.2) 14 NC_058416.1 (76527274..76531043, complement)
100 previous assembly ASM220157v1 (GCF_002201575.1) Unplaced Scaffold NW_018734397.1 (1828416..1832185)

Chromosome 14 - NC_058416.1Genomic Context describing neighboring genes Neighboring gene musashi RNA binding protein 1 Neighboring gene phospholipase A2 group IB Neighboring gene U4 spliceosomal RNA Neighboring gene U4 spliceosomal RNA

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD+ binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables NAD-dependent protein lysine deacetylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Neomonachus schauinslandi Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM220157v2

Genomic

  1. NC_058416.1 Reference ASM220157v2

    Range
    76527274..76531043 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044921141.1 → XP_044777076.1  NAD-dependent protein lipoamidase sirtuin-4, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8M1MT85
    Conserved Domains (1) summary
    cl00195
    Location:47 → 217
    SIR2; SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, ...

  2. XM_021703532.1 → XP_021559207.1  NAD-dependent protein lipoamidase sirtuin-4, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A2Y9I5G7
    Related
    ENSNSCP00000029678.1, ENSNSCT00000033385.1
    Conserved Domains (1) summary
    cd01409
    Location:47 → 308
    SIRT4; Eukaryotic and prokaryotic group (class2) which includes human sirtuin SIRT4 and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.