These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_001048194.2 → NP_001041659.1 regulator of chromosome condensation isoform a
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (a).
- Source sequence(s)
-
BC069198, BF590413, X12654
- Consensus CDS
-
CCDS41295.1
- UniProtKB/Swiss-Prot
-
P18754
- Related
- ENSP00000362937, OTTHUMP00000211005, ENST00000373831, OTTHUMT00000010324
- Conserved Domains (1) summary
-
- pfam00415
Location:394 – 445
Blast Score: 150
- RCC1; Regulator of chromosome condensation (RCC1) repeat
-
NM_001048195.2 → NP_001041660.1 regulator of chromosome condensation isoform b
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a.
- Source sequence(s)
-
BF590413, BM546148, BQ436549, X12654
- UniProtKB/TrEMBL
-
E9PAT9
- UniProtKB/Swiss-Prot
-
P18754
- Related
- ENSP00000413644, OTTHUMP00000211007, ENST00000411533, OTTHUMT00000010326
- Conserved Domains (2) summary
-
- COG5184
Location:21 – 435
Blast Score: 429
- ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]
- pfam00415
Location:380 – 431
Blast Score: 150
- RCC1; Regulator of chromosome condensation (RCC1) repeat
-
NM_001048199.2 → NP_001041664.1 regulator of chromosome condensation isoform c
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR and lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (c) that is shorter than isoform a. Both variants 3 and 4 encode the same isoform. This variant is a read-through transcript between the upstream non-coding SNHG3 locus (GeneID:8420) and the downstream RCC1 locus (GeneID:1104).
- Source sequence(s)
-
BC007300, BF590413, BF667678, BU501614
- Consensus CDS
-
CCDS323.1
- UniProtKB/Swiss-Prot
-
P18754
- UniProtKB/TrEMBL
-
Q5T081
- Related
- ENSP00000381931, ENST00000398958
- Conserved Domains (2) summary
-
- pfam00415
Location:363 – 414
Blast Score: 149
- RCC1; Regulator of chromosome condensation (RCC1) repeat
- pfam13540
Location:69 – 97
Blast Score: 78
- RCC1_2; Regulator of chromosome condensation (RCC1) repeat
-
NM_001269.4 → NP_001260.1 regulator of chromosome condensation isoform c
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (c) that is shorter than isoform a. Both variants 3 and 4 encode the same isoform.
- Source sequence(s)
-
BF590413, X12654
- Consensus CDS
-
CCDS323.1
- UniProtKB/Swiss-Prot
-
P18754
- UniProtKB/TrEMBL
-
Q5T081
- Related
- ENSP00000362938, OTTHUMP00000003775, ENST00000373832, OTTHUMT00000010321
- Conserved Domains (2) summary
-
- pfam00415
Location:363 – 414
Blast Score: 149
- RCC1; Regulator of chromosome condensation (RCC1) repeat
- pfam13540
Location:69 – 97
Blast Score: 78
- RCC1_2; Regulator of chromosome condensation (RCC1) repeat
RNA
-
NR_030725.1 RNA Sequence
- Description
- Transcript Variant: This variant (5) includes alternate 5' exon structure, compared to variant 1. This variant is a read-through transcript between the upstream non-coding SNHG3 locus (GeneID:8420) and the downstream RCC1 locus (GeneID:1104). This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to inhibit the translation of the longest ORF, as found in variant 1. Translation of the upstream ORF would render the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
BF590413, BF667678, BU622451, BX109495, CB985055, X06130
-
NR_030726.1 RNA Sequence
- Description
- Transcript Variant: This variant (6) includes alternate 5' exon structure, compared to variant 1. This variant is a read-through transcript between the upstream non-coding SNHG3 locus (GeneID:8420) and the downstream RCC1 locus (GeneID:1104). This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to inhibit the translation of the longest ORF, as found in variant 1. Translation of the upstream ORF would render the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
BC007300, BC036903, BF590413, BF667678, CB985055
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000001.10 Reference GRCh37.p5 Primary Assembly
- Range
- 28832455..28865708
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000133.1 Alternate HuRef
- Range
- 27086264..27119463
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)