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PLCB4 phospholipase C beta 4 [ Numida meleagris (helmeted guineafowl) ]

Gene ID: 110395536, updated on 15-Mar-2024

Summary

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Gene symbol
PLCB4
Gene description
phospholipase C beta 4
See related
Ensembl:ENSNMEG00000004968
Gene type
protein coding
RefSeq status
MODEL
Organism
Numida meleagris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Numididae; Numida
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
44
Annotation release Status Assembly Chr Location
100 current NumMel1.0 (GCF_002078875.1) 3 NC_034411.1 (13606473..13847922, complement)

Chromosome 3 - NC_034411.1Genomic Context describing neighboring genes Neighboring gene D-beta-hydroxybutyrate dehydrogenase, mitochondrial-like Neighboring gene p21 (RAC1) activated kinase 5 Neighboring gene lysosomal associated membrane protein family member 5 Neighboring gene phospholipase C beta 1 Neighboring gene thioredoxin related transmembrane protein 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034411.1 Chromosome 3 Reference NumMel1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Numida meleagris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NumMel1.0 Primary Assembly

Genomic

  1. NC_034411.1 Reference NumMel1.0 Primary Assembly

    Range
    13606473..13847922 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021390074.1 → XP_021245749.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    Conserved Domains (7) summary
    cd00275
    Location:714 → 830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:926 → 967
    DUF1154; Protein of unknown function (DUF1154)
    pfam11705
    Location:423 → 525
    RNA_pol_3_Rpc31; DNA-directed RNA polymerase III subunit Rpc31
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    cl26511
    Location:859 → 1173
    Neuromodulin_N; Gap junction protein N-terminal region

  2. XM_021390076.1 → XP_021245751.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X2

    Related
    ENSNMEP00000004727.1, ENSNMET00000008245.1
    Conserved Domains (7) summary
    cd00275
    Location:702 → 818
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 668
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:914 → 955
    DUF1154; Protein of unknown function (DUF1154)
    pfam11705
    Location:423 → 525
    RNA_pol_3_Rpc31; DNA-directed RNA polymerase III subunit Rpc31
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    cl26511
    Location:847 → 1161
    Neuromodulin_N; Gap junction protein N-terminal region

  3. XM_021390073.1 → XP_021245748.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    Related
    ENSNMEP00000004704.1, ENSNMET00000008215.1
    Conserved Domains (7) summary
    cd00275
    Location:714 → 830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:926 → 967
    DUF1154; Protein of unknown function (DUF1154)
    pfam11705
    Location:423 → 525
    RNA_pol_3_Rpc31; DNA-directed RNA polymerase III subunit Rpc31
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    cl26511
    Location:859 → 1173
    Neuromodulin_N; Gap junction protein N-terminal region

  4. XM_021390075.1 → XP_021245750.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    Conserved Domains (7) summary
    cd00275
    Location:714 → 830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:926 → 967
    DUF1154; Protein of unknown function (DUF1154)
    pfam11705
    Location:423 → 525
    RNA_pol_3_Rpc31; DNA-directed RNA polymerase III subunit Rpc31
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    cl26511
    Location:859 → 1173
    Neuromodulin_N; Gap junction protein N-terminal region

RNA

  1. XR_002436444.1 RNA Sequence

  2. XR_002436445.1 RNA Sequence

    Related
    ENSNMET00000008258.1
Nucleotide Protein
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