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Plcb4 phospholipase C, beta 4 [ Mus musculus (house mouse) ]

Gene ID: 18798, updated on 5-Mar-2024

Summary

Official Symbol
Plcb4provided by MGI
Official Full Name
phospholipase C, beta 4provided by MGI
Primary source
MGI:MGI:107464
See related
Ensembl:ENSMUSG00000039943 AllianceGenome:MGI:107464
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A930039J07Rik; C230058B11Rik
Summary
Predicted to enable mitogen-activated protein kinase binding activity and phosphatidylinositol phospholipase C activity. Involved in modulation of chemical synaptic transmission. Located in several cellular components, including glutamatergic synapse; parallel fiber to Purkinje cell synapse; and smooth endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human PLCB4 (phospholipase C beta 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in bladder adult (RPKM 32.1), cerebellum adult (RPKM 16.4) and 11 other tissues See more
Orthologs
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Genomic context

See Plcb4 in Genome Data Viewer
Location:
2 F3; 2 66.64 cM
Exon count:
49
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (135500523..135856522)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (135658603..136014602)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 9630028H03 gene Neighboring gene STARR-seq mESC enhancer starr_05784 Neighboring gene pluripotency associated transcript 3 Neighboring gene STARR-seq mESC enhancer starr_05788 Neighboring gene predicted gene, 54134 Neighboring gene STARR-seq mESC enhancer starr_05793 Neighboring gene predicted gene 14210 Neighboring gene STARR-seq mESC enhancer starr_05794 Neighboring gene STARR-seq mESC enhancer starr_05795 Neighboring gene predicted gene, 54133 Neighboring gene predicted gene, 26227 Neighboring gene lysosomal-associated membrane protein family, member 5

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables mitogen-activated protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables phosphatidylinositol phospholipase C activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4
NP_001342082.1
NP_001342083.1
NP_001342084.1
NP_001342085.1
NP_038857.1
XP_006498999.1
XP_006499000.1
XP_006499001.1
XP_006499002.1
XP_006499004.1
XP_006499006.1
XP_006499008.1
XP_006499009.1
XP_006499010.1
XP_006499011.1
XP_006499013.1
XP_011237659.1
XP_011237661.1
XP_030104392.1
XP_030104397.1
XP_030104399.1
XP_036015472.1
XP_036015477.1
XP_036015478.1
XP_036015483.1
XP_036015485.1
XP_036015489.1
XP_036015500.1
XP_036015503.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355153.1NP_001342082.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a).
    Source sequence(s)
    AL928798, AL929052, AL935301
    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8471194
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:702818
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312668
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:914955
    DUF1154; Protein of unknown function (DUF1154)
  2. NM_001355154.1NP_001342083.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and lacks an alternate 3' exon compared to variant 1, that causes a frameshift. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform (b).
    Source sequence(s)
    AL928798, AL935301
    Consensus CDS
    CCDS16788.1
    UniProtKB/TrEMBL
    Q91UZ1, V9GXQ9
    Related
    ENSMUSP00000038409.5, ENSMUST00000035646.11
    Conserved Domains (6) summary
    PTZ00121
    Location:8391170
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:702818
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312668
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:914955
    DUF1154; Protein of unknown function (DUF1154)
  3. NM_001355155.1NP_001342084.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) contains an alternate in-frame 5' exon and lacks an alternate 3' exon compared to variant 1, that causes a frameshift. The resulting isoform (c) has an alternate internal segment and a shorter and distinct C-terminus compared to isoform a.
    Source sequence(s)
    AL928798, AL929052, AL935301
    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8511182
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:714830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:926967
    DUF1154; Protein of unknown function (DUF1154)
  4. NM_001355156.1NP_001342085.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks an alternate 5' exon compared to variant 1. The resulting isoform (d) is shorter at the N-terminus compared to isoform a.
    Source sequence(s)
    AL928798, AL929052, AL935301
    Conserved Domains (4) summary
    PTZ00121
    Location:579926
    PTZ00121; MAEBL; Provisional
    cd08591
    Location:44400
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PLN02228
    Location:16539
    PLN02228; Phosphoinositide phospholipase C
    pfam06631
    Location:646687
    DUF1154; Protein of unknown function (DUF1154)
  5. NM_013829.3NP_038857.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform b

    See identical proteins and their annotated locations for NP_038857.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate 3' exon compared to variant 1, that causes a frameshift. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform (b).
    Source sequence(s)
    AL928798, AL929052, AL935301
    Consensus CDS
    CCDS16788.1
    UniProtKB/TrEMBL
    Q91UZ1, V9GXQ9
    Related
    ENSMUSP00000105736.2, ENSMUST00000110109.8
    Conserved Domains (6) summary
    PTZ00121
    Location:8391170
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:702818
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312668
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:914955
    DUF1154; Protein of unknown function (DUF1154)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    135500523..135856522
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011239359.4XP_011237661.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    See identical proteins and their annotated locations for XP_011237661.1

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8601207
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:715831
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312681
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:927968
    DUF1154; Protein of unknown function (DUF1154)
  2. XM_036159592.1XP_036015485.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X4

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8471194
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:702818
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312668
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:914955
    DUF1154; Protein of unknown function (DUF1154)
  3. XM_030248537.2XP_030104397.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X3

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8481195
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:703819
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312669
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:915956
    DUF1154; Protein of unknown function (DUF1154)
  4. XM_006498936.4XP_006498999.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    See identical proteins and their annotated locations for XP_006498999.1

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8601207
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:715831
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312681
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:927968
    DUF1154; Protein of unknown function (DUF1154)
  5. XM_006498941.2XP_006499004.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X5

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8521183
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:715831
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312681
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:927968
    DUF1154; Protein of unknown function (DUF1154)
  6. XM_006498943.3XP_006499006.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X6

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8401171
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:703819
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312669
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:915956
    DUF1154; Protein of unknown function (DUF1154)
  7. XM_011239357.4XP_011237659.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    See identical proteins and their annotated locations for XP_011237659.1

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8601207
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:715831
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312681
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:927968
    DUF1154; Protein of unknown function (DUF1154)
  8. XM_006498939.4XP_006499002.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X3

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8481195
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:703819
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312669
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:915956
    DUF1154; Protein of unknown function (DUF1154)
  9. XM_006498938.4XP_006499001.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X2

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8591206
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:714830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:926967
    DUF1154; Protein of unknown function (DUF1154)
  10. XM_036159579.1XP_036015472.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8601207
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:715831
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312681
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:927968
    DUF1154; Protein of unknown function (DUF1154)
  11. XM_036159584.1XP_036015477.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8601207
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:715831
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312681
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:927968
    DUF1154; Protein of unknown function (DUF1154)
  12. XM_036159610.1XP_036015503.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X11

    Conserved Domains (4) summary
    PTZ00121
    Location:591938
    PTZ00121; MAEBL; Provisional
    cd08591
    Location:44412
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PLN02228
    Location:16551
    PLN02228; Phosphoinositide phospholipase C
    pfam06631
    Location:658699
    DUF1154; Protein of unknown function (DUF1154)
  13. XM_036159585.1XP_036015478.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X2

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8591206
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:714830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:926967
    DUF1154; Protein of unknown function (DUF1154)
  14. XM_036159596.1XP_036015489.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X4

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8471194
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:702818
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312668
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:914955
    DUF1154; Protein of unknown function (DUF1154)
  15. XM_036159590.1XP_036015483.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X3

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8481195
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:703819
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312669
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:915956
    DUF1154; Protein of unknown function (DUF1154)
  16. XM_030248532.2XP_030104392.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8601207
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:715831
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312681
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:927968
    DUF1154; Protein of unknown function (DUF1154)
  17. XM_006498937.5XP_006499000.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    See identical proteins and their annotated locations for XP_006499000.1

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8601207
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:715831
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312681
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:927968
    DUF1154; Protein of unknown function (DUF1154)
  18. XM_030248539.2XP_030104399.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X4

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:8471194
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:702818
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312668
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:914955
    DUF1154; Protein of unknown function (DUF1154)
  19. XM_006498945.5XP_006499008.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X7

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (6) summary
    PTZ00121
    Location:7471094
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:602718
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:199568
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd16211
    Location:35187
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:814855
    DUF1154; Protein of unknown function (DUF1154)
    cl17171
    Location:130
    PH-like; Pleckstrin homology-like domain
  20. XM_036159607.1XP_036015500.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X10

    Conserved Domains (4) summary
    PTZ00121
    Location:592939
    PTZ00121; MAEBL; Provisional
    cd08591
    Location:44413
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PLN02228
    Location:16552
    PLN02228; Phosphoinositide phospholipase C
    pfam06631
    Location:659700
    DUF1154; Protein of unknown function (DUF1154)
  21. XM_006498947.5XP_006499010.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X8

    See identical proteins and their annotated locations for XP_006499010.1

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (5) summary
    PTZ00121
    Location:7171064
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:572688
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:169538
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd16211
    Location:5157
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:784825
    DUF1154; Protein of unknown function (DUF1154)
  22. XM_006498946.5XP_006499009.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X8

    See identical proteins and their annotated locations for XP_006499009.1

    UniProtKB/TrEMBL
    V9GXQ9
    Conserved Domains (5) summary
    PTZ00121
    Location:7171064
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:572688
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:169538
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd16211
    Location:5157
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:784825
    DUF1154; Protein of unknown function (DUF1154)
  23. XM_006498948.5XP_006499011.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X12

    Conserved Domains (6) summary
    PTZ00121
    Location:6931040
    PTZ00121; MAEBL; Provisional
    cd08591
    Location:145514
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PLN02228
    Location:117653
    PLN02228; Phosphoinositide phospholipase C
    cd15898
    Location:100133
    EFh_PI-PLC; EF-hand motif [structural motif]
    cl28895
    Location:82133
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    pfam06631
    Location:760801
    DUF1154; Protein of unknown function (DUF1154)
  24. XM_006498950.4XP_006499013.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X9

    Conserved Domains (6) summary
    PTZ00121
    Location:613960
    PTZ00121; MAEBL; Provisional
    cd08591
    Location:65434
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PLN02228
    Location:37573
    PLN02228; Phosphoinositide phospholipase C
    cd15898
    Location:2053
    EFh_PI-PLC; EF-hand motif [structural motif]
    cl28895
    Location:253
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    pfam06631
    Location:680721
    DUF1154; Protein of unknown function (DUF1154)