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SIRT3 sirtuin 3 [ Panthera pardus (leopard) ]

Gene ID: 109259795, updated on 14-Mar-2024

Summary

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Gene symbol
SIRT3
Gene description
sirtuin 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera pardus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_02 current ASM2436296v1 (GCF_024362965.1) Unplaced Scaffold NW_026526677.1 (61962..81873, complement)
100 previous assembly PanPar1.0 (GCF_001857705.1) Unplaced Scaffold NW_017620058.1 (54231..75373, complement)

NW_026526677.1Genomic Context describing neighboring genes Neighboring gene Bet1 golgi vesicular membrane trafficking protein like Neighboring gene RIC8 guanine nucleotide exchange factor A Neighboring gene proteasome 26S subunit, non-ATPase 13 Neighboring gene uncharacterized LOC109259798

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD+ binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_024362965.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM2436296v1 Primary Assembly

Genomic

  1. NW_026526677.1 Reference ASM2436296v1 Primary Assembly

    Range
    61962..81873 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019437603.2 → XP_019293148.1  NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A9V1F0W4
    Conserved Domains (1) summary
    cl00195
    Location:69 → 283
    SIR2; SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, ...

  2. XM_019437602.2 → XP_019293147.1  NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A9V1F0V5
    Conserved Domains (1) summary
    cd01408
    Location:111 → 346
    SIRT1; Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins ...

  3. XM_053899254.1 → XP_053755229.1  NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A9W2V9H5

  4. XM_053899253.1 → XP_053755228.1  NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A9W2V9H5

  5. XM_053899252.1 → XP_053755227.1  NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A9W2V9H5

  6. XM_053899251.1 → XP_053755226.1  NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A9W2V9H5

  7. XM_053899250.1 → XP_053755225.1  NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A9W2V9S1
Nucleotide Protein
Heading Accession and Version

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