U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ERBB2 erb-b2 receptor tyrosine kinase 2 [ Miniopterus natalensis ]

Gene ID: 107529006, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Gene symbol
ERBB2
Gene description
erb-b2 receptor tyrosine kinase 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Miniopterus natalensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Miniopteridae; Miniopterus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
100 current Mnat.v1 (GCF_001595765.1) Unplaced Scaffold NW_015504321.1 (539133..555307, complement)

NW_015504321.1Genomic Context describing neighboring genes Neighboring gene growth factor receptor bound protein 7 Neighboring gene migration and invasion enhancer 1 Neighboring gene post-GPI attachment to proteins phospholipase 3 Neighboring gene phenylethanolamine N-methyltransferase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_015504321.1 Unplaced Scaffold Reference Mnat.v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basal plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
receptor tyrosine-protein kinase erbB-2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Miniopterus natalensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mnat.v1

Genomic

  1. NW_015504321.1 Reference Mnat.v1

    Range
    539133..555307 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016202269.1 → XP_016057755.1  receptor tyrosine-protein kinase erbB-2

    Conserved Domains (8) summary
    cd12094
    Location:611 → 644
    TM_ErbB2; Transmembrane domain of ErbB2, a Protein Tyrosine Kinase
    smart00261
    Location:527 → 573
    FU; Furin-like repeats
    cd00064
    Location:205 → 250
    FU; Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
    cd05109
    Location:682 → 960
    PTKc_HER2; Catalytic domain of the Protein Tyrosine Kinase, HER2
    pfam00757
    Location:159 → 308
    Furin-like; Furin-like cysteine rich region
    pfam01030
    Location:22 → 143
    Recep_L_domain; Receptor L domain
    pfam07714
    Location:690 → 946
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14843
    Location:481 → 613
    GF_recep_IV; Growth factor receptor domain IV
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.