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SIRT1 sirtuin 1 [ Rousettus aegyptiacus (Egyptian rousette) ]

Gene ID: 107501303, updated on 30-Mar-2024

Summary

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Gene symbol
SIRT1
Gene description
sirtuin 1
Locus tag
HJG63_017618
Gene type
protein coding
RefSeq status
MODEL
Organism
Rousettus aegyptiacus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Rousettinae; Rousettus
Orthologs
human mouse all
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Genomic context

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See SIRT1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
101 current mRouAeg1.p (GCF_014176215.1) Unplaced Scaffold NW_023416309.1 (17876697..17905816, complement)
100 previous assembly Raegyp2.0 (GCF_001466805.2) Unplaced Scaffold NW_015495085.1 (19325..48379)

NW_023416309.1Genomic Context describing neighboring genes Neighboring gene HECT and RLD domain containing E3 ubiquitin protein ligase 4 Neighboring gene 5S ribosomal RNA Neighboring gene 5S ribosomal RNA Neighboring gene eukaryotic translation initiation factor 3 subunit L-like Neighboring gene DnaJ heat shock protein family (Hsp40) member C12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD+ binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NAD-dependent protein deacetylase sirtuin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rousettus aegyptiacus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRouAeg1.p

Genomic

  1. NW_023416309.1 Reference mRouAeg1.p

    Range
    17876697..17905816 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016127316.2 → XP_015982802.2  NAD-dependent protein deacetylase sirtuin-1 isoform X1

    UniProtKB/TrEMBL
    A0A7J8GFF8
    Conserved Domains (1) summary
    cd01408
    Location:244 → 479
    SIRT1; Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins ...

  2. XM_036223501.1 → XP_036079394.1  NAD-dependent protein deacetylase sirtuin-1 isoform X2

    UniProtKB/TrEMBL
    A0A7J8GFC9
    Conserved Domains (1) summary
    cl00195
    Location:12 → 186
    SIR2; SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, ...
Nucleotide Protein
Heading Accession and Version

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